Consolidated Statements of Operations and Comprehensive Loss - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2020	Dec. 31, 2019
Consolidated Statements of Operations and Comprehensive Loss [Abstract]
Revenues	$ 45,849	$ 52,609
Costs and expenses:
Manufacture and supply	12,964	20,361
Research and development	19,886	20,574
Selling, general and administrative	55,892	64,342
Total costs and expenses	88,742	105,277
Loss from operations	(42,893)	(52,668)
Other income (expenses):
Interest expense	(11,064)	(9,318)
Interest expense related to the sale of future revenue	(1,958)	0
Interest income and other income (expense), net	132	636
Loss on the extinguishment of debt	0	(4,896)
Net loss before income taxes	(55,783)	(66,246)
Income taxes	0	0
Net loss	(55,783)	(66,246)
Comprehensive loss	$ (55,783)	$ (66,246)
Net loss per share - basic and diluted (in dollars per share)	$ (1.66)	$ (2.61)
Weighted-average number of common shares outstanding - basic and diluted (in shares)	33,651,127	25,356,098