Consolidated Statements of Operations and Comprehensive Loss - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2019	Dec. 31, 2018
Consolidated Statements of Operations and Comprehensive Loss [Abstract]
Revenues	$ 52,609	$ 67,430
Costs and expenses:
Manufacture and supply	20,361	20,988
Research and development	20,574	23,112
Selling, general and administrative	64,342	72,269
Total costs and expenses	105,277	116,369
Loss from operations	(52,668)	(48,934)
Other income/(expenses):
Interest expense	(9,318)	(7,711)
Interest income	636	552
Loss on the extinguishment of debt	(4,896)	0
Change in fair value of warrant	0	(5,278)
Net loss before income taxes	(66,246)	(61,376)
Income taxes	0	0
Net loss	(66,246)	(61,376)
Comprehensive loss	$ (66,246)	$ (61,376)
Net loss per share - basic and diluted (in dollars per share)	$ (2.61)	$ (2.96)
Weighted-average number of common shares outstanding - basic and diluted (in shares)	25,356,098	20,725,526