Summary of Significant Accounting Policies (Details) - USD ($) $ in Thousands	Mar. 31, 2019	Dec. 31, 2018
New Accounting Pronouncements or Change in Accounting Principle [Line Items]
Deferred revenue	$ 3,105	$ 3,762
Deferred revenue, current portion	700	721
Deferred revenue, non-current portion	2,405	0
ASU 2014-09 and ASU 2018-07 [Member]
New Accounting Pronouncements or Change in Accounting Principle [Line Items]
Cumulative effect adjustment of accumulated deficit		(2,832)
ASU 2014-09 [Member] | Adjustments Due to Adoption of ASU 2014-09 [Member]
New Accounting Pronouncements or Change in Accounting Principle [Line Items]
Deferred revenue	(2,683)	3,100
Deferred revenue, current portion	(278)
Deferred revenue, non-current portion	$ (2,405)
ASU 2014-09 [Member] | Adjustments Due to Adoption of ASU 2014-09 [Member] | Manufacture and Supply Revenue [Member]
New Accounting Pronouncements or Change in Accounting Principle [Line Items]
Deferred revenue		(151)
ASU 2014-09 [Member] | Adjustments Due to Adoption of ASU 2014-09 [Member] | Co-Development and Research Fees [Member]
New Accounting Pronouncements or Change in Accounting Principle [Line Items]
Deferred revenue		(117)
Additional Paid-in Capital [Member] | ASU 2014-09 and ASU 2018-07 [Member]
New Accounting Pronouncements or Change in Accounting Principle [Line Items]
Cumulative effect adjustment of accumulated deficit		20
Retained Earnings/Accumulated Deficit [Member] | ASU 2014-09 and ASU 2018-07 [Member]
New Accounting Pronouncements or Change in Accounting Principle [Line Items]
Cumulative effect adjustment of accumulated deficit		$ (2,852)