X0508 4 2025-07-29 0000004962 AMERICAN EXPRESS CO AXP 0001397707 McNeal Glenda G 200 VESEY STREET NEW YORK NY 10285 1 Chief Partner Officer 0 Common Stock 2025-07-29 4 M 0 50000 65.43 A 60957.498 D Common Stock 2025-07-29 4 S 0 17609 309.27 D 43348.498 D Common Stock 2025-07-29 4 S 0 32391 309.62 D 10957.498 D Employee Stock Option (Right to Buy) 65.43 2025-07-29 4 M 0 50000 0 D 2026-04-29 Common Stock 50000 0 D Includes shares acquired pursuant to dividend reinvestment. The price reported in Column 4 is a weighted average price, rounded to the nearest cent. These shares were sold in multiple transactions at prices ranging from $308.94 to $309.52. The reporting person undertakes to provide to American Express Company, any security holder of American Express Company, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within this range. The price reported in Column 4 is a weighted average price, rounded to the nearest cent. These shares were sold in multiple transactions at prices ranging from $309.52 to $310.20. The reporting person undertakes to provide to American Express Company, any security holder of American Express Company, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within this range. The option vested in three installments based upon the satisfaction of performance criteria specified for the award at the time of grant: 60% on April 29, 2018, 20% on April 29, 2019 and 20% on April 29, 2020. Exhibit 24: Power of Attorney /s/ James J. Killerlane III, attorney in-fact 2025-07-31