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Income Taxes - Narrative (Details) - USD ($)
12 Months Ended
Dec. 31, 2020
Dec. 31, 2019
Dec. 31, 2018
Dec. 31, 2017
Operating Loss Carryforwards [Line Items]        
Increase (decrease) in deferred tax asset valuation allowance $ 22,163,000 $ 12,826,000    
Percent maximum of federal taxable income to offset with net operating losses 80.00%      
Unrecognized tax benefits $ 2,019,000 1,436,000 $ 1,348,000 $ 615,000
Unrecognized tax benefits that would impact effective tax rate 0      
Unrecognized tax benefits, income tax penalties and interest expense 0 $ 0 $ 0  
Domestic Tax Authority        
Operating Loss Carryforwards [Line Items]        
Operating loss carryforwards 241,908,000      
State and Local Jurisdiction        
Operating Loss Carryforwards [Line Items]        
Operating loss carryforwards 209,771,000      
Research Tax Credit Carryforward | Domestic Tax Authority        
Operating Loss Carryforwards [Line Items]        
Research and development tax credits 6,275,000      
Research Tax Credit Carryforward | State and Local Jurisdiction        
Operating Loss Carryforwards [Line Items]        
Research and development tax credits $ 3,463,000