X0306 4 2021-05-10 0 0001357874 PRECISION BIOSCIENCES INC DTIL 0001397607 Schinazi Raymond F C/O PRECISION BIOSCIENCES, INC. 302 E. PETTIGREW STREET, SUITE A-100 DURHAM NC 27701 1 0 0 0 Stock Option (Right to Buy) 8.07 2021-05-10 4 A 0 32800 0.00 A 2031-05-09 Common Stock 32800 32800 D The option vests on the earlier of May 10, 2022 or the day immediately prior to the date of the next annual meeting of the Company's stockholders occurring after May 10, 2021, subject to the Reporting Person's continued service to the Issuer through the applicable vesting date. /s/ Dario Scimeca, Attorney-in-Fact for Raymond F. Schinazi 2021-05-12