The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
Aeglea Common 00773J103 1,934 240,500 SH   DFND   240,500 0 0
Avedro Common 05355N109 8,734 719,402 SH   DFND   719,402 0 0
Chiasma Common 16706W102 10,694 2,080,595 SH   DFND   2,080,595 0 0
Crispr NAMEN AKT H17182108 41,826 1,171,268 SH   DFND   1,171,268 0 0
Cymabay Common 23257D103 1,739 131,036 SH   DFND   131,036 0 0
Histogenics Common 43358V109 206 1,777,778 SH   DFND   1,777,778 0 0
Obseva Common H5861P103 1,118 87,999 SH   DFND   87,999 0 0
Paratek Common 699374302 5,591 1,041,131 SH   DFND   1,041,131 0 0
Proteon Common 74371L109 1,009 2,017,872 SH   DFND   2,017,872 0 0
Realm ADR 75606L103 988 255,371 SH   DFND   255,371 0 0
Sientra Common 82621J105 20,466 2,390,843 SH   DFND   2,390,843 0 0
Sierra Oncology Common 82640U107 2,307 1,365,027 SH   DFND   1,365,027 0 0
Soleno Common 834203200 9,619 4,669,272 SH   DFND   4,669,272 0 0
Verona SPONDS ADR 925050106 5,502 901,943 SH   DFND   901,943 0 0