Consolidated Balance Sheets - USD ($) $ in Thousands	Dec. 31, 2021	Dec. 31, 2020
Current assets:
Cash and cash equivalents	$ 585,578	$ 99,957
Short-term available-for-sale investments	70,831	421,705
Accounts receivable, net	96,318	53,046
Inventories, net	98,550	64,650
Prepaid expenses and other current assets	14,771	12,265
Total current assets	866,048	651,623
Long-term available-for-sale investments	0	95,459
Fixed assets, net	188,401	136,688
Right-of-use assets, net	76,410	74,492
Goodwill	145,175	99,547
Intangible assets, net	623,968	96,521
Deferred tax assets	153,364	106,164
Investments and other assets	21,987	14,019
Total assets	2,075,353	1,274,513
Current liabilities:
Accounts payable	10,543	10,431
Accrued expenses	127,555	70,974
Lease liabilities	7,891	7,425
Convertible senior notes, net	350,466	149,648
Contingent consideration	0	14,736
Current portion of long-term debt, net	24,234	0
Income taxes payable	429	114
Total current liabilities	521,118	253,328
Convertible senior notes, net	339,267	313,030
Lease liabilities	71,727	71,025
Deferred revenue	10,125	0
Long-term debt, net	335,263	0
Contingent consideration	57,598	13,610
Other liabilities	9,847	3,832
Total liabilities	1,344,945	654,825
Commitments and contingencies (Note 21)
Stockholders’ equity:
Preferred stock, par value $0.001; 5,000,000 shares authorized; none issued and outstanding at December 31, 2021 and 2020	0	0
Common stock, par value $0.001; 250,000,000 shares authorized; 44,734,308 and 43,636,929 shares issued and outstanding at December 31, 2021 and 2020, respectively	45	44
Additional paid-in capital	942,091	873,201
Accumulated deficit	(211,895)	(253,875)
Accumulated other comprehensive income	167	318
Total stockholders’ equity	730,408	619,688
Total liabilities and stockholders’ equity	$ 2,075,353	$ 1,274,513