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Cover - USD ($)
$ in Millions
 12 Months Ended
Dec. 31, 2021
Feb. 27, 2022
Jun. 30, 2021
Cover [Abstract]      
Document Type 10-K    
Document Annual Report true    
Document Period End Date Dec. 31, 2021    
Document Transition Report false    
Entity File Number 001-35060    
Entity Registrant Name PACIRA BIOSCIENCES, INC.    
Entity Incorporation, State or Country Code DE    
Entity Tax Identification Number 51-0619477    
Entity Address, Address Line One 5401 West Kennedy Boulevard, Suite 890    
Entity Address, City or Town Tampa,    
Entity Address, State or Province FL    
Entity Address, Postal Zip Code 33609    
City Area Code (813)    
Local Phone Number 553-6680    
Title of 12(b) Security Common Stock, par value $0.001 per share    
Trading Symbol PCRX    
Security Exchange Name NASDAQ    
Entity Well-known Seasoned Issuer Yes    
Entity Voluntary Filers No    
Entity Current Reporting Status Yes    
Entity Interactive Data Current Yes    
Entity Filer Category Large Accelerated Filer    
Entity Small Business false    
Entity Emerging Growth Company false    
ICFR Auditor Attestation Flag true    
Entity Shell Company false    
Entity Public Float     $ 1,600.0
Entity Common Stock, Shares Outstanding   44,847,728  
Documents Incorporated by Reference
DOCUMENTS INCORPORATED BY REFERENCE
Part III of this Annual Report on Form 10-K incorporates certain information by reference from the registrant’s proxy statement for the 2022 annual meeting of stockholders to be filed with the Securities and Exchange Commission no later than 120 days after the end of the registrant’s fiscal year ended December 31, 2021.
    
Entity Central Index Key 0001396814    
Amendment Flag false    
Current Fiscal Year End Date --12-31    
Document Fiscal Year Focus 2021    
Document Fiscal Period Focus FY