X0306 4 2021-02-18 0000318154 AMGEN INC AMGN 0001396482 Bradway Robert A ONE AMGEN CENTER DRIVE THOUSAND OAKS CA 91320-1799 1 1 Chairman, CEO and President Common Stock 2021-02-18 4 M 0 73500 54.69 A 618380 D Common Stock 2021-02-18 4 F 0 47527 235.61 D 570853 D Nqso (Right to Buy) 54.69 2021-02-18 4 M 0 73500 0 D 2013-04-25 2021-04-25 Common Stock 73500 0 D Non-market exercise of a total of 73,500 stock options expiring April 25, 2021 wherein 47,527 shares, in the aggregate, issuable pursuant to the exercise of these options were withheld by the Company to cover the option exercise price and tax withholding, with the remaining shares delivered to the reporting person. These shares include the following RSUs granted under the Company's equity plans: 5,019 RSUs which vest on 5/1/2021; 9,439 RSUs which vest in installments of 4,649 on 4/27/2021 and 4,790 on 4/27/2022; 15,791 RSUs which vest in two installments of 5,211 on 5/3/2021 and 5/3/2022 and one installment of 5,369 on 5/3/2023; and 12,184 RSUs which vest in installments of 4,020 on 5/05/2022, 4,021 on 5/5/2023 and 4,143 on 5/5/2024. Vested RSUs will be paid in shares of the Company's common stock on a one-to-one basis. These shares include 2,382 Dividend Equivalents (DEs) granted pursuant to the Amgen Inc. 2009 Amended and Restated Equity Incentive Plan and subject to a qualifying dividend reinvestment plan. DEs are credited on the reporting person's unvested RSUs and are paid out in shares of the Company's common stock on a one-to-one basis according to the vesting schedule, along with a cash payment for any remaining fractional share amount. /s/ Robert A. Bradway 2021-02-21