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CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS (Unaudited) - USD ($)
$ in Thousands
6 Months Ended
Jun. 30, 2025
Jun. 30, 2024
CASH FLOWS FROM OPERATING ACTIVITIES:    
Net loss $ (156,693) $ (140,463)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation 0 6
Accretion of investments (6,810) (7,470)
Non-cash operating lease expense 393 486
Stock-based compensation 24,167 18,795
Amortization of debt issuance costs 167 0
Changes in operating assets and liabilities:    
Accounts receivable (11,852) 0
Inventory (17,107) 0
Prepaid expenses and other assets (4,778) (890)
Collaboration (payable) receivable, net (31,547) (4,129)
Other receivable 6 (9,582)
Accounts payable 5,727 1,607
Accrued expenses and other liabilities 15,370 (13,553)
Net cash used in operating activities (182,957) (155,193)
CASH FLOWS FROM INVESTING ACTIVITIES:    
Purchases of short and long-term investments (102,251) (167,385)
Proceeds from sales and maturities of short-term investments 238,280 129,736
Net cash provided by (used in) investing activities 136,029 (37,649)
CASH FLOWS FROM FINANCING ACTIVITIES:    
Proceeds from Employee Stock Purchase Plan 1,013 546
Proceeds from stock option exercises 468 2,298
Net cash provided by financing activities 1,481 2,844
NET DECREASE CASH, CASH EQUIVALENTS AND RESTRICTED CASH (45,447) (189,998)
CASH, CASH EQUIVALENTS AND RESTRICTED CASH—beginning of period 154,300 295,611
CASH, CASH EQUIVALENTS AND RESTRICTED CASH —end of period $ 108,853 $ 105,613