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The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP FIGI (to the nearest dollar) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
Equillium, Inc. COM 29446K106   1,259,234 1,824,977 SH   DFND   1,824,977 0 0
Ovid Therapeutics Inc. COM 690469101   4,421,750 5,750,000 SH   DFND   5,750,000 0 0
Ovid Therapeutics Inc. COM 690469101   1,370,711 1,781,996 SH   SOLE   1,781,996 0 0
Xilio Therapeutics, Inc. COM 98422T100   1,398,415 1,475,121 SH   DFND   1,475,121 0 0
Turnstone Biologics Corp. COM 90042W100   2,347,060 895,824 SH   DFND   895,824 0 0
Shattuck Labs, Inc. COM 82024L103   1,990,289 515,619 SH   DFND   515,619 0 0
Denali Therapeutics Inc. COM 24823R105   97,862,060 4,214,559 SH   SOLE   4,214,559 0 0
Wave Life Sciences Ltd. SHS Y95308105   1,247,500 250,000 SH   DFND   250,000 0 0
Wave Life Sciences Ltd. SHS Y95308105   5,473,491 1,096,892 SH   SOLE   1,096,892 0 0
Phathom Pharmaceuticals, Inc. COM 71722W107   16,037,749 1,557,063 SH   SOLE   1,557,063 0 0
Rani Therapeutics Holdings, Inc. COM CL A 753018100   817,654 215,172 SH   DFND   215,172 0 0
Akili, Inc. COMMON STOCK 00974B107   321,386 738,819 SH   DFND   738,819 0 0
HilleVax, Inc. COM 43157M102   97,229,440 6,724,000 SH   DFND 1 6,724,000 0 0
STANDARD BIOTOOLS INC. COM 34385P108   29,232 16,515 SH   DFND   16,515 0 0
American Well Corp COM CL A NEW 03044L204   505,267 1,554,669 SH   DFND   1,554,669 0 0