X0206 3 2017-08-01 0 0001183765 Molecular Templates, Inc. MTEM 0001002637 MILLENNIUM PHARMACEUTICALS INC 40 LANDSDOWNE STREET CAMBRIDGE MA 02139 0 0 1 0 0001688140 Takeda Pharmaceuticals International AG THURGAUERSTRASSE 130, 8152 GLATTPARK V8 SWITZERLAND 0 0 1 0 0001716226 Takeda Pharma A/S LANGEBJERG 1, 4000 ROSKILDE G7 DENMARK 0 0 1 0 0001716380 Takeda A/S DYBENDAL ALLE 10, 2630 TAASTRUP G7 DENMARK 0 0 1 0 0001716379 Takeda Europe Holdings B.V. JUPITERSTRAAT 250, 2132 HK HOOFDDORP P7 NETHERLANDS 0 0 1 0 0001395064 TAKEDA PHARMACEUTICAL CO LTD 12-10, NIHONBASHI 2-CHOME, CHUO-KU TOKYO M0 103-8668 JAPAN 0 0 1 0 0001716229 Takeda Pharmaceuticals U.S.A., Inc. ONE TAKEDA PARKWAY DEERFIELD IL 60015 0 0 1 0 Common Stock 2922993 D These shares are owned directly by Millennium Pharmaceuticals, Inc. ("Millennium"). Millennium is a wholly-owned direct subsidiary of Takeda Pharmaceuticals U.S.A., Inc. ("Takeda USA"). Takeda Pharmaceutical Company Limited ("Takeda") owns 73.37% of Takeda USA, and Takeda Pharmaceuticals International AG ("Takeda International") owns 26.63% of Takeda USA. Takeda Pharma A/S ("Takeda Denmark") owns 86.83% of Takeda International, and Takeda Europe Holdings B.V. ("Takeda Europe") owns 13.17% of Takeda International. Takeda Denmark is a wholly-owned direct subsidiary of Takeda A/S. Takeda owns 76.09% of Takeda A/S, and Takeda Europe owns 23.91% of Takeda A/S. Takeda Europe is a wholly-owned direct subsidiary of Takeda. Takeda, Takeda USA, Takeda International, Takeda Denmark, Takeda A/S and Takeda Europe each disclaims beneficial ownership of such shares except to the extent of its pecuniary interest therein. Exhibit List: Exhibit 24.1 Power of Attorney for Millennium Pharmaceuticals, Inc.; Exhibit 24.2 Power of Attorney for Takeda Pharmaceuticals U.S.A., Inc.; Exhibit 24.3 Power of Attorney for Takeda Pharmaceuticals International AG; Exhibit 24.4 Power of Attorney for Takeda Pharma A/S; Exhibit 24.5 Power of Attorney for Takeda A/S; Exhibit 24.6 Power of Attorney for Takeda Europe Holdings B.V. /s/ James Kehoe, Chief Financial Officer, Takeda Pharmaceutical Company Limited 2017-09-08 /s/ Brett R. Budzinski, Attorney-in-Fact for Millennium Pharmaceuticals, Inc. 2017-09-08 /s/ Brett R. Budzinski, Attorney-in-Fact for Takeda Pharmaceuticals U.S.A., Inc. 2017-09-08 /s/ Brett R. Budzinski, Attorney-in-Fact for Takeda Pharmaceutical International AG 2017-09-08 /s/ Brett R. Budzinski, Attorney-in-Fact for Takeda Pharma A/S 2017-09-08 /s/ Brett R. Budzinski, Attorney-in-Fact for Takeda A/S 2017-09-08 /s/ Brett R. Budzinski, Attorney-in-Fact for Takeda Europe Holdings B.V. 2017-09-08