X0306 4 2016-02-10 0 0000906709 NEKTAR THERAPEUTICS NKTR 0001394875 Labrucherie Gil M C/O NEKTAR THERAPEUTICS 455 MISSION BAY BOULEVARD SOUTH SAN FRANCISCO CA 94158 0 1 0 0 SVP & General Counsel Common Stock 2016-02-10 4 M 0 11666 6.46 A 16917 D Common Stock 2016-02-10 4 S 0 11666 11.49 D 5251 D Stock Option 6.46 2016-02-10 4 M 0 11666 0.00 D 2012-02-25 2016-02-24 Common Stock 11666 0 D This transaction was made pursuant to a Rule 10b5-1 trading plan for stock options scheduled to expire in early 2016 as described in the Current Report on Form 8-K filed by Nektar Therapeutics on July 16, 2015. This transaction was executed in multiple trades at prices ranging from $11.16 to $11.75. The price reported above reflects the weighted average sale price. The reporting person hereby undertakes to provide full information regarding the number of shares and the prices at which the transactions were effected upon request to the SEC staff, the issuer, or a security holder of the issuer. Gil M. Labrucherie 2016-02-12