X0306 4 2022-03-07 0 0001393584 American Well Corp AMWL 0001824217 Knight Kurt C/O AMERICAN WELL CORPORATION 75 STATE STREET, 26TH FLOOR BOSTON MA 02109 0 1 0 0 Chief Operating Officer Class A Common Stock 2022-03-07 4 S 0 25850 3.6728 D 1568159 D The sale reported in this Form 4 was effected pursuant to the terms of a Rule 10b5-1 trading plan adopted by the reporting person on September 9, 2021, as amended, and was made in order to pay the tax liability arising from the vesting and settlement of restricted stock units on March 5, 2022. /s/ Bradford Gay as attorney-in-fact for Kurt Knight 2022-03-08