X0306 4 2021-06-05 0 0001393584 American Well Corp AMWL 0001824217 Knight Kurt C/O AMERICAN WELL CORPORATION 75 STATE STREET, 26TH FLOOR BOSTON MA 02109 0 1 0 0 Chief Operating Officer Class A Common Stock 2021-06-05 4 S 0 25850 13.1993 D 1439544 D The sale reported in this Form 4 was effected pursuant to the terms of a Rule 10b5-1 trading plan adopted by the reporting person on December 23, 2020, as amended on February 1, 2021 and further amended on April 14, 2021, and was made in order to pay the tax liability arising from the vesting and settlement of restricted stock units on June 5, 2021. /s/ Bradford Gay as attorney-in-fact for Kurt Knight 2021-06-08