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Income Taxes - Reconciliation of Federal Income Tax Rate (Details) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2024
Dec. 31, 2023
Dec. 31, 2022
Income Taxes      
Income tax benefit $ 0 $ 0 $ 0
Reconciliation of the U.S. federal statutory income tax rate to the Company's effective income tax rate      
Federal statutory income tax rate 21.00% 21.00% 21.00%
Research and development tax credits 3.50% 3.60% 5.40%
State taxes, net of federal benefit 1.80% 2.00% 2.60%
Stock-based compensation (1.90%) (2.30%) (2.10%)
Derivative liability     2.70%
Change in tax rate   (0.40%) 1.40%
Debt extinguishment (1.90%)    
Other (1.10%) (0.20%) (0.10%)
Change in valuation allowance (21.40%) (23.70%) (30.90%)