Stock-Based Awards - Stock Incentive Plan (Details)							12 Months Ended
	Jun. 12, 2024 shares	Jun. 14, 2023 shares	Jan. 01, 2023 shares	Jun. 16, 2022 shares	Jun. 18, 2021 shares	Dec. 10, 2020 shares	Dec. 31, 2014 shares	Dec. 31, 2024 item shares	Oct. 04, 2024 shares	Oct. 03, 2024 shares	Apr. 16, 2024 shares	Apr. 15, 2024 shares	Feb. 20, 2024 shares	Feb. 19, 2024 shares	Jan. 01, 2024 shares	Dec. 31, 2023 item shares	Dec. 31, 2021 shares	Jan. 01, 2015 shares
Stock-Based Awards
Number of stock based compensation plans | item								3								3
Number of shares of common stock reserved for issuance								9,260,579
2014 and 2006 Stock Incentive Plan
Stock-Based Awards
Granted (in shares)							0
Number of shares of common stock available for issuance																	9,766,336
2014 Stock Incentive Plan
Stock-Based Awards
Granted (in shares)					0
Number of shares of common stock available for issuance								456,334
2021 Incentive Plan
Stock-Based Awards
Number of shares of common stock reserved for issuance								6,000,000
Additional number of shares authorized for issuance	7,000,000	3,900,000		3,600,000
Number of shares of common stock available for issuance								8,019,151
2019 Inducement Plan
Stock-Based Awards
Number of shares of common stock authorized for issuance						1,054,000			6,054,000	4,804,000	4,804,000	3,804,000	3,804,000	1,054,000
Additional number of shares authorized for issuance						554,000
Number of shares of common stock available for issuance								848,373
2014 ESPP
Stock-Based Awards
Number of shares of common stock available for issuance															606,186	398,784
2014 ESPP | Common Stock
Stock-Based Awards
Number of shares of common stock reserved for issuance																		207,402
Additional number of shares authorized for issuance			207,402
Number of shares of common stock available for issuance								393,055