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Nature of the Business and Basis of Presentation - Nature of Business (Details) - USD ($)
$ in Thousands
Dec. 31, 2019
Dec. 31, 2018
Dec. 31, 2017
Nature of the Business and Basis of Presentation      
Cash and cash equivalents $ 54,437 $ 54,062 $ 41,538
Accumulated deficit $ 383,615 $ 297,243