X0306 4 2016-08-24 0 0001393020 Invuity, Inc. IVTY 0001034251 SAWYER PHILIP M C/O INVUITY, INC. 444 DE HARO STREET SAN FRANCISCO CA 94107 1 1 0 0 President and CEO Common Stock 2016-08-24 4 M 0 17224 1.295 A 17224 D Common Stock 2016-08-24 4 M 0 24776 1.295 A 42000 D Common Stock 2016-08-24 4 S 0 42000 13.0272 D 0 D Common Stock 216600 I See footnote Employee Stock Option (right to buy) 1.295 2016-08-24 4 M 0 17224 0.00 D 2020-03-17 Common Stock 17224 77220 D Employee Stock Option (right to buy) 1.295 2016-08-24 4 M 0 24776 0.00 D 2020-11-17 Common Stock 24776 89584 D The option shares were exercised pursuant to the Rule 10b5-1 trading plan entered into by the Reporting Person on November 30, 2015 (the "Trading Plan"). The shares were sold pursuant to the Trading Plan. This transaction was executed in multiple trades at prices ranging from $13.00 to $13.12. The price reported above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. The shares are held by Helix Founders Fund, L.P. ("HFF"). HFF GP, LLC is the General Partner of HFF, and Helix Ventures, LLC ("Helix Ventures") is the management company of HFF. The Reporting Person is a General Partner of Helix Ventures and disclaims beneficial ownership of shares held by HFF, except to the extent of his pecuniary interest therein. The Reporting Person exercised 17,224 shares of the option originally for 94,444 shares and which option vested as to one-fourth of the shares on February 22, 2011 and as to one forty-eighth of the shares each month thereafter. The Reporting Person exercised 24,776 shares of the option originally for 114,360 shares and which option vested as to one-fourth of the shares on February 22, 2011 and as to one forty-eighth of the shares each month thereafter. /s/ Nancy Hargreaves, by power of attorney 2016-08-25