Summary of Information Associated with Outstanding and Exercisable Stock Options (Detail) - $ / shares	12 Months Ended
	Dec. 31, 2016	Dec. 31, 2015
Share Based Compensation Shares Authorized Under Stock Option Plans Exercise Price Range [Line Items]
Options Outstanding, Number of Options	16,915	24,089
Options Outstanding, Weighted- Average Exercise Price	$ 289.73	$ 535.80
Options Outstanding, Weighted- Average Remaining Contractual Life in Years	7 years 6 months 15 days
Options Exercisable, Number of Options	9,095
Options Exercisable, Weighted- Average Exercise Price	$ 504.80
Options Exercisable, Weighted- Average Remaining Contractual Life in Years	6 years 7 months 10 days
Range One
Share Based Compensation Shares Authorized Under Stock Option Plans Exercise Price Range [Line Items]
Range of Exercise Prices, Lower Range	$ 0.00
Range of Exercise Prices, Upper Range	$ 51.00
Options Outstanding, Number of Options	14,450
Options Outstanding, Weighted- Average Exercise Price	$ 40.62
Options Outstanding, Weighted- Average Remaining Contractual Life in Years	8 years 7 months 10 days
Options Exercisable, Number of Options	6,630
Options Exercisable, Weighted- Average Exercise Price	$ 41.68
Options Exercisable, Weighted- Average Remaining Contractual Life in Years	8 years 6 months 29 days
Range Two
Share Based Compensation Shares Authorized Under Stock Option Plans Exercise Price Range [Line Items]
Range of Exercise Prices, Lower Range	$ 105.00
Range of Exercise Prices, Upper Range	$ 147.00
Options Outstanding, Number of Options	80
Options Outstanding, Weighted- Average Exercise Price	$ 144.90
Options Outstanding, Weighted- Average Remaining Contractual Life in Years	3 months 26 days
Options Exercisable, Number of Options	80
Options Exercisable, Weighted- Average Exercise Price	$ 144.90
Options Exercisable, Weighted- Average Remaining Contractual Life in Years	3 months 26 days
Range Three
Share Based Compensation Shares Authorized Under Stock Option Plans Exercise Price Range [Line Items]
Range of Exercise Prices, Lower Range	$ 264.00
Range of Exercise Prices, Upper Range	$ 438.00
Options Outstanding, Number of Options	586
Options Outstanding, Weighted- Average Exercise Price	$ 368.79
Options Outstanding, Weighted- Average Remaining Contractual Life in Years	5 months 9 days
Options Exercisable, Number of Options	586
Options Exercisable, Weighted- Average Exercise Price	$ 368.87
Options Exercisable, Weighted- Average Remaining Contractual Life in Years	5 months 9 days
Range Four
Share Based Compensation Shares Authorized Under Stock Option Plans Exercise Price Range [Line Items]
Range of Exercise Prices, Lower Range	$ 462.00
Range of Exercise Prices, Upper Range	$ 1,845.00
Options Outstanding, Number of Options	801
Options Outstanding, Weighted- Average Exercise Price	$ 715.51
Options Outstanding, Weighted- Average Remaining Contractual Life in Years	2 years 3 months 22 days
Options Exercisable, Number of Options	801
Options Exercisable, Weighted- Average Exercise Price	$ 715.51
Options Exercisable, Weighted- Average Remaining Contractual Life in Years	2 years 3 months 22 days
Range Five
Share Based Compensation Shares Authorized Under Stock Option Plans Exercise Price Range [Line Items]
Range of Exercise Prices, Lower Range	$ 2,331.00
Range of Exercise Prices, Upper Range	$ 3,426.00
Options Outstanding, Number of Options	637
Options Outstanding, Weighted- Average Exercise Price	$ 2,938.98
Options Outstanding, Weighted- Average Remaining Contractual Life in Years	4 months 21 days
Options Exercisable, Number of Options	637
Options Exercisable, Weighted- Average Exercise Price	$ 2,938.98
Options Exercisable, Weighted- Average Remaining Contractual Life in Years	4 months 21 days
Range Six
Share Based Compensation Shares Authorized Under Stock Option Plans Exercise Price Range [Line Items]
Range of Exercise Prices, Lower Range	$ 3,801.00
Range of Exercise Prices, Upper Range	$ 5,742.00
Options Outstanding, Number of Options	361
Options Outstanding, Weighted- Average Exercise Price	$ 4,556.47
Options Outstanding, Weighted- Average Remaining Contractual Life in Years	2 years 3 months 4 days
Options Exercisable, Number of Options	361
Options Exercisable, Weighted- Average Exercise Price	$ 4,556.47
Options Exercisable, Weighted- Average Remaining Contractual Life in Years	2 years 3 months 4 days