Note 11 - Stock-based Compensation

9 Months Ended

Sep. 30, 2020

Notes to Financial Statements

Share-based Payment Arrangement [Text Block]

11.

Stock-Based Compensation

The Company records stock-based compensation expense during the requisite service period for share-based payment awards granted to employees and non-employees.

The following table sets forth the Company's stock-based compensation expense (in thousands) for the periods indicated:

	Three Months Ended September 30,				Nine Months Ended September 30,
	2020		2019		2020			2019
Restricted stock
Research and development	$	142	$	68	$	353		$	129
Selling, general and administrative		500		236		1,122			581
Stock appreciation rights
Research and development		16		132		(61	)		114
Selling, general and administrative		16		132		(67	)		114
Total stock-based compensation	$	674	$	568	$	1,347		$	938

Stock Option Award Activity

. Stock option activity under the Company's stock incentive plans at

September 30, 2020

and changes during the

three

months ended

September 30, 2020

were as follows:

						Weighted-
						Average
				Weighted-		Remaining
				Average		Contractual		Aggregate
	Number of			Exercise		Term		Intrinsic
	Options			Price (1)		(years)		Value
Options outstanding at December 31, 2019		1,561		$	928.79		6.56	$	—
Granted		—		$	—
Canceled or forfeited		(9	)	$	72,891.04
Exercised		—		$	—
Options outstanding at September 30, 2020		1,552		$	556.13		5.83	$	—
Options exercisable at September 30, 2020		1,552		$	556.13		5.83	$	—
Options vested and expected to vest at September 30, 2020		1,552		$	556.13		5.83	$	—

(

1

)  Exercise price of options outstanding range from

$20.00

to

$99,300.00

as of

September 30, 2020.

Restricted Stock

. Non-vested restricted stock awards at

September 30, 2020

and changes during the

three

months ended

September 30, 2020

were as follows:

				Weighted-
				Average
	Number of			Grant-Date
	Shares			Fair Value
Non-vested at December 31, 2019		1,308,613		$	1.91
Granted		4,454,046		$	0.63
Vested		(1,015,336	)	$	1.47
Canceled or forfeited		(6,974	)	$	1.90
Non-vested at September 30, 2020		4,740,349		$	0.80

The total fair value of restricted stock that vested during the

nine

months ended

September 30, 2020

totaled

$1.5

 million. As of

September 30, 2020,

the total unrecognized compensation expense, net of estimated forfeitures, relating to restricted stock awards was

$3.1

 million, which is expected to be recognized over the remaining weighted-average period of approximately

1.6

 years.