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Note 10 - Stock-based Compensation
3 Months Ended
Mar. 31, 2018
Notes to Financial Statements  
Disclosure of Compensation Related Costs, Share-based Payments [Text Block]
10.
Stock-Based Compensation
 
The Company records stock-based compensation expense during the requisite service period for share-based payment awards granted to employees and non-employees.
 
The following table sets forth the Company’s stock-based compensation expense (in thousands) for the periods indicated.
 
 
   
Three Months Ended March 31,
 
   
2018
   
2017
 
Stock options and employee stock purchase plan awards
               
Research and development
  $
9
    $
9
 
Selling, general and administrative
   
30
     
30
 
                 
Restricted stock awards
               
Research and development
   
     
12
 
Selling, general and administrative
   
     
17
 
                 
Restricted stock units
               
Research and development
   
17
     
18
 
Selling, general and administrative
   
41
     
42
 
Total stock-based compensation
  $
97
    $
128