X0303 4/A 2011-04-13 2011-04-15 0 0001390478 RXI PHARMACEUTICALS CORP RXII 0001297696 Hillsberg Sanford C/O RXI PHARMACEUTICALS CORPORATION 60 PRESCOTT STREET WORCESTER MA 01605 1 0 0 0 Common Stock 2011-04-13 4 A 0 120838 A 126838 D The number of shares initally report to have been received pursuant to the Merger was incorrect. Received in exchange for 993,739 shares of Apthera, Inc. common stock in connection with merger of Apthers, Inc. into RXI Pharmaceuticals Corporation (the "Merger"). On the effective date of the Merger, the closing price of RXI Pharmaceuticals Corporation common stock was $1.275 per share. /s/Marc A. Rubenstein, Attorney-in-Fact 2011-04-21