| | | | Very truly yours, | |
| | | |
Angelos M. Stergiou, M.D., Sc.D. h.c.
President and Chief Executive Officer |
|
| | | | By Order of the Board of Directors, | |
| | | |
Angelos M. Stergiou, M.D., Sc.D. h.c.
|
|
| | | | President and Chief Executive Officer | |
| | |
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By Internet: Please follow the instructions on the proxy card or voting instructions sent to you. Your vote must be received by 11:59 p.m. Eastern Time on Wednesday, June 19, 2024, to be counted.
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By Telephone: To vote over the telephone, dial the number listed on the proxy card or voting instructions sent to you, and follow the instructions. Your vote must be received by 11:59 p.m. Eastern Time on Wednesday, June 19, 2024, to be counted.
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By Proxy by Mail: Mark, sign, and date your proxy card and mail the proxy to the address stated on the proxy card. If you return your signed proxy card to us before the 2024 Annual Meeting, we will vote your shares as you direct.
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Proposal 1:
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| | To elect two (2) Class II directors to serve on the Company’s Board of Directors for a three-year term expiring in 2027. | |
|
Proposal 2:
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| | To ratify the appointment by our Audit Committee of Moss Adams LLP as our independent registered public accounting firm for the fiscal year ending December 31, 2024. | |
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Proposal 3:
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| | To approve, on a non-binding advisory basis, the compensation of our named executive officers. | |
Name of Beneficial Owner
|
| |
Number
|
| |
Percentage of
Shares Beneficially Owned |
| ||||||
5% or Greater Stockholders: | | | | | | | | | | | | | |
Entities affiliated with Anson Advisors, Inc and Anson Funds
Management LP |
| | | | 4,286,619(1) | | | | | | 7.6% | | |
Directors and Executive Officers: | | | | | | | | | | | | | |
Angelos M. Stergiou, President, Chief Executive Officer and Director
|
| | | | 402,415(2) | | | | | | * | | |
Barbara A. Wood, Former Executive Vice President, General Counsel and Corporate Secretary
|
| | | | 142,717(3) | | | | | | * | | |
John T. Burns, Senior Vice President, Chief Financial Officer
|
| | | | 98,866(4) | | | | | | | | |
Jane Wasman, Chair of the Board
|
| | | | 35,855(5) | | | | | | * | | |
David A. Scheinberg, Director
|
| | | | 36,037(6) | | | | | | * | | |
Robert L. Van Nostrand, Director
|
| | | | 35,855(5) | | | | | | * | | |
John Varian, Director
|
| | | | 35,855(5) | | | | | | * | | |
Katherine Bach Kalin, Director
|
| | | | 32,900(7) | | | | | | * | | |
All current executive officers and directors as a group (7 persons)
|
| | | | 677,783 | | | | | | 1.2 | | |
Name
|
| |
Age
|
| |
Position
|
| |
Term
Expires |
| |
Audit
Committee |
| |
Compensation
Committee |
| |
Nominating
and Corporate Governance Committee |
| |
Science
Committee |
| ||||||||||||
Jane Wasman | | |
67
|
| | Chair of the Board | | |
2026
|
| | | | ✔ | | | | | | | | | | | | ✔* | | | | | | | | |
Angelos M. Stergiou | | |
48
|
| |
Director, President and
Chief Executive Officer |
| |
2025
|
| | | | | | | | | | | | | | | | | | | | | | ✔ | | |
David A. Scheinberg | | |
68
|
| | Director | | |
2024
|
| | | | | | | | | | ✔ | | | | | | | | | | | | ✔* | | |
Robert L. Van Nostrand | | |
67
|
| | Director | | |
2026
|
| | | | ✔* | | | | | | | | | | | | ✔ | | | | | | | | |
John Varian | | |
64
|
| | Director | | |
2025
|
| | | | ✔ | | | | | | ✔* | | | | | | | | | | | | ✔ | | |
Katherine Bach Kalin | | |
61
|
| | Director | | |
2024
|
| | | | | | | | | | ✔ | | | | | | ✔ | | | | | | | | |
Name
|
| |
Age
|
| |
Position with the Company
|
|
Angelos M. Stergiou, M.D., Sc.D. h.c.
|
| |
48
|
| | President, Chief Executive Officer and Director | |
John T. Burns | | |
39
|
| | Senior Vice President, Chief Financial Officer | |
Name
|
| |
Year
|
| |
Salary
($) |
| |
Non-Equity
Incentive Plan Compensation ($)(3) |
| |
Bonus
($) |
| |
Option
Awards ($)(1) |
| |
Stock
Awards ($)(2) |
| |
All Other
Compensation ($) |
| |
Total
($) |
| ||||||||||||||||||||||||
Angelos M. Stergiou, M.D., Sc.D. h.c.
President and Chief Executive Officer |
| | | | 2023 | | | | | | 625,000 | | | | | | 275,000 | | | | | | — | | | | | | 654,675 | | | | | | 193,720 | | | | | | 4,243(5) | | | | | | 1,752,638 | | |
| | | 2022 | | | | | | 593,500 | | | | | | 326,425 | | | | | | — | | | | | | 795,300 | | | | | | 234,960 | | | | | | 2,060(5) | | | | | | 1,952,245 | | | ||
Barbara Wood, Esq.
Former Executive Vice President, General Counsel and Corporate Secretary |
| | | | 2023 | | | | | | 442,000 | | | | | | 146,744 | | | | | | — | | | | | | 240,800 | | | | | | 66,800 | | | | | | 17,576(7) | | | | | | 913,920 | | |
| | | 2022 | | | | | | 425,000 | | | | | | 173,400 | | | | | | 20,000(4) | | | | | | 234,975 | | | | | | 69,420 | | | | | | 14,260(8) | | | | | | 937,055 | | | ||
John T. Burns
Senior Vice President, Chief Financial Officer |
| | | | 2023 | | | | | | 365,000 | | | | | | 125,560 | | | | | | — | | | | | | 225,750 | | | | | | 66,800 | | | | | | 14,598(7) | | | | | | 797,708 | | |
| | | 2022 | | | | | | 310,000 | | | | | | 111,800 | | | | | | — | | | | | | 173,520 | | | | | | 52,264 | | | | | | 13,260(8) | | | | | | 659,844 | | |
Name
|
| |
Grant
Date |
| |
Number of
Securities Underlying Unexercised Options Exercisable |
| |
Number of
Securities Underlying Unexercised Options (#) Unexercisable(1) |
| |
Option
Exercise Price ($)(2) |
| |
Option
Expiration Date |
| |
Number of
Shares or Units of Stock That Have Not Vested (#)(3) |
| |
Market
Value of Shares or Units of Stock That Have Not Vested ($)(4) |
| |||||||||||||||||||||
Angelos M. Stergiou
|
| | | | 03/13/2018 | | | | | | 1,900 | | | | | | — | | | | | $ | 262.00 | | | | | | 03/13/2028 | | | | | | — | | | | | | — | | |
| | | 03/18/2019 | | | | | | 8,500 | | | | | | — | | | | | $ | 69.00 | | | | | | 03/18/2029 | | | | | | — | | | | | | — | | | ||
| | | 03/12/2020 | | | | | | 65,625 | | | | | | 4,375 | | | | | $ | 1.89 | | | | | | 03/12/2030 | | | | | | — | | | | | | — | | | ||
| | | 03/12/2020 | | | | | | — | | | | | | — | | | | | | — | | | | | | — | | | | | | 95,000 | | | | | $ | 100,700 | | | ||
| | | 03/04/2021 | | | | | | 81,469 | | | | | | 37,031 | | | | | $ | 8.00 | | | | | | 03/04/2031 | | | | | | — | | | | | | — | | | ||
| | | 03/04/2021 | | | | | | — | | | | | | — | | | | | | — | | | | | | — | | | | | | 4,937 | | | | | $ | 5,233 | | | ||
| | | 01/31/2022 | | | | | | 79,063 | | | | | | 85,938 | | | | | $ | 5.34 | | | | | | 01/31/2032 | | | | | | — | | | | | | — | | | ||
| | | 01/31/2022 | | | | | | — | | | | | | — | | | | | | — | | | | | | — | | | | | | 22,000 | | | | | $ | 23,320 | | | ||
| | | 02/02/2023 | | | | | | — | | | | | | 217,500 | | | | | $ | 3.34 | | | | | | 02/02/2033 | | | | | | — | | | | | | — | | | ||
| | | 02/02/2023 | | | | | | — | | | | | | — | | | | | | — | | | | | | — | | | | | | 43,500 | | | | | $ | 46,110 | | | ||
Barbara A. Wood
|
| | | | 03/14/2018 | | | | | | 1,000 | | | | | | — | | | | | $ | 255.00 | | | | | | 03/14/2028 | | | | | | — | | | | | | — | | |
| | | 03/18/2019 | | | | | | 3,300 | | | | | | — | | | | | $ | 69.00 | | | | | | 03/18/2029 | | | | | | — | | | | | | — | | | ||
| | | 03/12/2020 | | | | | | 23,438 | | | | | | 1,563 | | | | | $ | 1.89 | | | | | | 03/12/2030 | | | | | | — | | | | | | — | | | ||
| | | 03/12/2020 | | | | | | — | | | | | | — | | | | | | — | | | | | | — | | | | | | 35,000 | | | | | $ | 37,100 | | | ||
| | | 03/04/2021 | | | | | | 32,484 | | | | | | 14,766 | | | | | $ | 8.00 | | | | | | 03/04/2031 | | | | | | — | | | | | | — | | | ||
| | | 03/04/2021 | | | | | | — | | | | | | — | | | | | | — | | | | | | — | | | | | | 1,968 | | | | | $ | 2,086 | | | ||
| | | 01/31/2022 | | | | | | 23,359 | | | | | | 25,391 | | | | | $ | 5.34 | | | | | | 01/31/2032 | | | | | | — | | | | | | — | | | ||
| | | 01/31/2022 | | | | | | — | | | | | | — | | | | | | — | | | | | | — | | | | | | 6,500 | | | | | $ | 6,890 | | | ||
| | | 02/02/2023 | | | | | | — | | | | | | 80,000 | | | | | $ | 3.34 | | | | | | 02/02/2033 | | | | | | — | | | | | | — | | | ||
| | | 02/02/2023 | | | | | | — | | | | | | — | | | | | | — | | | | | | — | | | | | | 15,000 | | | | | $ | 15,900 | | | ||
John T. Burns
|
| | | | 03/13/2018 | | | | | | 400 | | | | | | — | | | | | $ | 262.00 | | | | | | 03/14/2028 | | | | | | — | | | | | | — | | |
| | | 03/18/2019 | | | | | | 1,800 | | | | | | — | | | | | $ | 69.00 | | | | | | 03/18/2029 | | | | | | — | | | | | | — | | | ||
| | | 03/12/2020 | | | | | | 9,375 | | | | | | 625 | | | | | $ | 1.89 | | | | | | 03/12/2030 | | | | | | — | | | | | | — | | | ||
| | | 03/12/2020 | | | | | | — | | | | | | — | | | | | | — | | | | | | — | | | | | | 15,000 | | | | | $ | 15,900 | | | ||
| | | 03/04/2021 | | | | | | 11,859 | | | | | | 5,391 | | | | | $ | 8.00 | | | | | | 03/04/2031 | | | | | | — | | | | | | — | | | ||
| | | 03/04/2021 | | | | | | — | | | | | | — | | | | | | — | | | | | | — | | | | | | 718 | | | | | $ | 761 | | | ||
| | | 01/31/2022 | | | | | | 17,250 | | | | | | 18,750 | | | | | $ | 5.34 | | | | | | 01/31/2032 | | | | | | — | | | | | | — | | | ||
| | | 01/31/2022 | | | | | | — | | | | | | — | | | | | | — | | | | | | — | | | | | | 4,800 | | | | | $ | 5,088 | | | ||
| | | 02/02/2023 | | | | | | — | | | | | | 75,000 | | | | | $ | 3.34 | | | | | | 02/02/2033 | | | | | | — | | | | | | — | | | ||
| | | 02/02/2023 | | | | | | — | | | | | | — | | | | | | — | | | | | | — | | | | | | 15,000 | | | | | $ | 15,900 | | |
Year(a)
|
| |
Summary
Compensation Table Total for PEO(b) |
| |
Compensation
Actually Paid to PEO(c) |
| |
Average
Summary Compensation Table Total for Non-PEO NEOs(d) |
| |
Average
Compensation Actually Paid to Non-PEO NEOs(e) |
| |
Value of Initial
Fixed $100 Investment Based On Total Shareholder Return(f) |
| |
Net Loss
(thousands)(g) |
| ||||||||||||||||||
2023
|
| | | $ | 1,752,638 | | | | | $ | 801,284 | | | | | $ | 855,814 | | | | | | 536,561 | | | | | | 44.92 | | | | | $ | (37,340) | | |
2022
|
| | | $ | 1,952,245 | | | | | $ | 667,297 | | | | | $ | 995,219 | | | | | | 514,536 | | | | | | 42.68 | | | | | $ | (41,301) | | |
2021
|
| | | $ | 1,833,917 | | | | | $ | 1,615,812 | | | | | $ | 911,937 | | | | | | 935,768 | | | | | | 95.18 | | | | | $ | (20,699) | | |
Year
|
| |
Reported
Summary Comp Table Total for PEO |
| |
Reported
Value of Equity Awards(1) |
| |
Equity
Award Adjustments(2) |
| |
Compensation
Actually Paid to PEO |
| ||||||||||||
2023
|
| | | $ | 1,752,638 | | | | | $ | (848,395) | | | | | $ | (102,959) | | | | | $ | 801,284 | | |
2022
|
| | | $ | 1,952,245 | | | | | $ | (1,030,260) | | | | | $ | (254,688) | | | | | $ | 667,297 | | |
2021
|
| | | $ | 1,833,917 | | | | | $ | (985,887) | | | | | $ | 767,782 | | | | | $ | 1,615,812 | | |
Year
|
| |
Year End
Fair Value of Outstanding and Unvested Equity Awards Granted in the Year |
| |
Year over
Year Change in Fair Value of Outstanding and Unvested Equity Awards Granted in Prior Years |
| |
Fair Value as
of Vesting Date of Equity Awards Granted and Vested in the Year |
| |
Year over
Year Change in Fair Value of Equity Awards Granted in Prior Years that Vested in the Year |
| |
Total Equity
Award Adjustments |
| |||||||||||||||
2023
|
| | | $ | 238,628 | | | | | $ | (315,187) | | | | | $ | 15,660 | | | | | $ | (42,060) | | | | | $ | (102,959) | | |
2022
|
| | | $ | 413,468 | | | | | $ | (606,744) | | | | | $ | 28,600 | | | | | $ | (90,012) | | | | | $ | (254,688) | | |
2021
|
| | | $ | 666,308 | | | | | $ | (46,816) | | | | | $ | 31,057 | | | | | $ | 117,233 | | | | | $ | 767,782 | | |
Year
|
| |
Average Reported
Summary Compensation Table Total for Non-PEO NEOs |
| |
Average Reported
Value of Equity Awards(1) |
| |
Average Equity Award
Adjustments(2) |
| |
Average Compensation
Actually Paid to Non-PEO NEOs |
| ||||||||||||
2023
|
| | | $ | 855,814 | | | | | $ | (300,075) | | | | | $ | (19,178) | | | | | $ | 536,561 | | |
2022
|
| | | $ | 995,219 | | | | | $ | (388,187) | | | | | $ | (92,496) | | | | | $ | 514,536 | | |
2021
|
| | | $ | 911,937 | | | | | $ | (393,107) | | | | | $ | 416,938 | | | | | $ | 935,768 | | |
Year
|
| |
Average
Year End Fair Value of Outstanding and Unvested Equity Awards Granted in the Year |
| |
Year over
Year Average Change in Fair Value of Outstanding and Unvested Equity Awards Granted in Prior Years |
| |
Fair Value as
of Vesting Date of Equity Awards Granted and Vested in the Year |
| |
Year over
Year Average Change in Fair Value of Equity Awards Granted in Prior Years that Vested in the Year |
| |
Total Average
Equity Award Adjustments |
| |||||||||||||||
2023
|
| | | $ | 69,008 | | | | | $ | (82,509) | | | | | $ | 5,400 | | | | | $ | (11,077) | | | | | $ | (19,178) | | |
2022
|
| | | $ | 163,465 | | | | | $ | (229,926) | | | | | $ | 8,450 | | | | | $ | (34,484) | | | | | $ | (92,496) | | |
2021
|
| | | $ | 265,680 | | | | | $ | 82,467 | | | | | $ | 12,383 | | | | | $ | 56,408 | | | | | $ | 416,938 | | |
Name
|
| |
Fees Earned or
Paid in Cash ($)(1) |
| |
Option
Awards ($)(2) |
| |
Stock Awards
($)(3) |
| |
Total
($)(4) |
| ||||||||||||
Jane Wasman
|
| | | | 99,780 | | | | | | 28,151 | | | | | | 8,350 | | | | | | 136,281 | | |
Robert L. Van Nostrand
|
| | | | 69,780 | | | | | | 28,151 | | | | | | 8,350 | | | | | | 106,281 | | |
John Varian
|
| | | | 74,000 | | | | | | 28,151 | | | | | | 8,350 | | | | | | 110,501 | | |
David A. Scheinberg
|
| | | | 66,000 | | | | | | 28,151 | | | | | | 8,350 | | | | | | 102,501 | | |
Katherine Bach Kalin
|
| | | | 56,000 | | | | | | 28,151 | | | | | | 8,350 | | | | | | 92,501 | | |
Compensation Category
|
| |
Amount
|
| |||
Annual Base Compensation
|
| | | $ | 40,000 | | |
Additional Non-Executive Chair Compensation
|
| | | $ | 30,000 | | |
Additional Committee Chair Compensation: | | | | | | | |
Audit
|
| | | $ | 18,000 | | |
Compensation
|
| | | $ | 18,000 | | |
Nominating and Corporate Governance
|
| | | $ | 18,000 | | |
Science
|
| | | $ | 18,000 | | |
Additional Committee Membership Compensation:
|
| | | $ | 18,000 | | |
Audit
|
| | | $ | 8,000 | | |
Compensation
|
| | | $ | 8,000 | | |
Nominating and Corporate Governance
|
| | | $ | 8,000 | | |
Science
|
| | | $ | 8,000 | | |
Plan Category
|
| |
Number of Securities to be
Issued upon Exercise of Outstanding Options, Warrants and Rights |
| |
Weighted
Average Exercise Price of Outstanding Options, Warrants and Rights |
| |
Number of Securities
Remaining Available for Future Issuance under Equity Compensation Plans (Excluding Securities Reflected in Previous Columns) |
| |||||||||
Equity compensation plans approved by security holders
|
| | | | | | | | | | | | | | | | | | |
2017 Equity Incentive Plan
|
| | | | 21,520 | | | | | $ | 112.85 | | | | | | — | | |
2023 Amended and Restated Equity Incentive Plan Stock
|
| | | | 1,923,424 | | | | | $ | 4.47(1) | | | | | | 3,950,528 | | |
2021 Employee Stock Purchase Plan
|
| | | | — | | | | | | N/A | | | | | | 183,457 | | |
Equity compensation plans not approved by
security holders |
| | | | | | | | | | | | | | | | | | |
None
|
| | | | | | | | | | | | | | | | | | |
Total
|
| | | | 21,520 | | | | | | 112.85 | | | | | | — | | |
| | |
2023
|
| |
2022
|
| ||||||
| | |
(in thousands)
|
| |||||||||
Audit Fees(1)
|
| | | $ | 457 | | | | | $ | 416 | | |
Audit-related Fees(2)
|
| | | | 103 | | | | | | 187 | | |
Tax Fees(3)
|
| | | | 33 | | | | | | 37 | | |
All Other Fees
|
| | | | — | | | | | | — | | |
Total Fees
|
| | | $ | 593 | | | | | $ | 640 | | |
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