<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0203</schemaVersion>

    <documentType>3</documentType>

    <periodOfReport>2010-06-27</periodOfReport>

    <noSecuritiesOwned>0</noSecuritiesOwned>

    <issuer>
        <issuerCik>0001340752</issuerCik>
        <issuerName>Molecular Insight Pharmaceuticals, Inc.</issuerName>
        <issuerTradingSymbol>MIPI</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001390113</rptOwnerCik>
            <rptOwnerName>Taconic Capital Advisors LP</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>450 PARK AVENUE</rptOwnerStreet1>
            <rptOwnerStreet2>9TH FLOOR</rptOwnerStreet2>
            <rptOwnerCity>NEW YORK</rptOwnerCity>
            <rptOwnerState>NY</rptOwnerState>
            <rptOwnerZipCode>10022</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>1</isOther>
            <officerTitle></officerTitle>
            <otherText>Reference Footnote 1</otherText>
        </reportingOwnerRelationship>
    </reportingOwner>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001495681</rptOwnerCik>
            <rptOwnerName>Taconic Associates LLC</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>450 PARK AVENUE, 9TH FLOOR</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>NEW YORK</rptOwnerCity>
            <rptOwnerState>NY</rptOwnerState>
            <rptOwnerZipCode>10022</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>1</isOther>
            <officerTitle></officerTitle>
            <otherText>Reference Footnote 1</otherText>
        </reportingOwnerRelationship>
    </reportingOwner>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001390110</rptOwnerCik>
            <rptOwnerName>Taconic Capital Advisors UK LLP</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>450 PARK AVENUE</rptOwnerStreet1>
            <rptOwnerStreet2>9TH FLOOR</rptOwnerStreet2>
            <rptOwnerCity>NEW YORK</rptOwnerCity>
            <rptOwnerState>NY</rptOwnerState>
            <rptOwnerZipCode>10022</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>1</isOther>
            <officerTitle></officerTitle>
            <otherText>Reference Footnote 1</otherText>
        </reportingOwnerRelationship>
    </reportingOwner>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001222668</rptOwnerCik>
            <rptOwnerName>BRODY KENNETH D</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>450 PARK AVENUE</rptOwnerStreet1>
            <rptOwnerStreet2>9TH FLOOR</rptOwnerStreet2>
            <rptOwnerCity>NEW YORK</rptOwnerCity>
            <rptOwnerState>NY</rptOwnerState>
            <rptOwnerZipCode>10022</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>1</isOther>
            <officerTitle></officerTitle>
            <otherText>Reference Footnote 1</otherText>
        </reportingOwnerRelationship>
    </reportingOwner>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001048891</rptOwnerCik>
            <rptOwnerName>BROSENS FRANK</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>450 PARK AVENUE</rptOwnerStreet1>
            <rptOwnerStreet2>9TH FLOOR</rptOwnerStreet2>
            <rptOwnerCity>NEW YORK</rptOwnerCity>
            <rptOwnerState>NY</rptOwnerState>
            <rptOwnerZipCode>10022</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>1</isOther>
            <officerTitle></officerTitle>
            <otherText>Reference footnote 1</otherText>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeHolding>
            <securityTitle>
                <value>Common Stock, par value $0.01 per share</value>
            </securityTitle>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>0</value>
                    <footnoteId id="F1"/>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>See Footnote</value>
                    <footnoteId id="F1"/>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeHolding>
    </nonDerivativeTable>

    <derivativeTable>
        <derivativeHolding>
            <securityTitle>
                <value>Warrant for Common Stock</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>5.87</value>
            </conversionOrExercisePrice>
            <exerciseDate>
                <value>2007-11-16</value>
            </exerciseDate>
            <expirationDate>
                <value>2012-11-16</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock, par value $0.01 per share</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>762691</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>See Footnotes</value>
                    <footnoteId id="F2"/>
                    <footnoteId id="F3"/>
                    <footnoteId id="F4"/>
                </natureOfOwnership>
            </ownershipNature>
        </derivativeHolding>
    </derivativeTable>

    <footnotes>
        <footnote id="F1">Not Applicable as Reporting Persons do not beneficially own any non-derivative securities of the Issuer. See Footnotes 2, 3 and 4.</footnote>
        <footnote id="F2">The Reporting Persons may be deemed to be a member of a &quot;group&quot; with certain other holders of equity securities and/or derivative securities of the Issuer for purposes of Section 13(d) of the Securities Exchange Act of 1934, as amended.  If such a group were determined to exist, the members hold in the aggregate more than ten percent (10%) of the Issuer's equity securities.  Each of the Reporting Persons disclaims the existence of such a group and disclaims beneficial ownership of any of the securities and/or derivative securities of the Issuer to which this Form 3 relates for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, except to the extent of such Reporting Person's pecuniary interest in the securities.</footnote>
        <footnote id="F3">This Form 3 relates to the securities held for the account of the Taconic Opportunity Fund L.P. (&quot;Taconic Opportunity Fund&quot;).  Taconic Capital Advisors L.P. (&quot;Taconic Advisors&quot;) and Taconic Capital Advisors UK LLP (&quot;Taconic Advisors UK&quot;) serve as the investment managers to the Taconic Opportunity Fund.  Taconic Capital Performance Partners LLC (&quot;Taconic Partners&quot;) serves as the general partner to Taconic Advisors.  Taconic Associates LLC (&quot;Taconic Associates&quot;) serves as the general partner to the Taconic Opportunity Fund.</footnote>
        <footnote id="F4">Mr.  Brody is a principal of Taconic Advisors, a director of Taconic Capital Services UK Ltd., the managing member of Taconic Advisors UK, and a manager of Taconic Partners and Taconic Associates. Mr. Brosens is a principal of Taconic Advisors, a director of Taconic Capital Services UK Ltd., the manager member of Taconic Advisors UK, and a manager of Taconic Partners and Taconic Associates.  As such, Taconic Advisors, Taconic Advisors UK, Taconic Associates, Mr. Brody, and Mr. Brosens may be deemed to have voting and dispositive power over the securities held for the account of the Taconic Opportunity Fund.</footnote>
    </footnotes>

    <remarks></remarks>

    <ownerSignature>
        <signatureName>TACONIC CAPITAL ADVISORS L.P. By: /s/ Kenneth D. Brody</signatureName>
        <signatureDate>2010-07-01</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>TACONIC CAPITAL ADVISORS UK LLP By: /s/ Kenneth D. Brody</signatureName>
        <signatureDate>2010-07-01</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>TACONIC ASSOCIATES LLC By: /s/ Kenneth D. Brody</signatureName>
        <signatureDate>2010-07-01</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>KENNETH D. BRODY By: /s/ Kenneth D. Brody</signatureName>
        <signatureDate>2010-07-01</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>FRANK P. BROSENS By: /s/ Frank P. Brosens</signatureName>
        <signatureDate>2010-07-01</signatureDate>
    </ownerSignature>
</ownershipDocument>
