0001389933-26-000004.txt : 20260515 0001389933-26-000004.hdr.sgml : 20260515 20260515132557 ACCESSION NUMBER: 0001389933-26-000004 CONFORMED SUBMISSION TYPE: 13F-HR PUBLIC DOCUMENT COUNT: 2 CONFORMED PERIOD OF REPORT: 20260331 FILED AS OF DATE: 20260515 DATE AS OF CHANGE: 20260515 EFFECTIVENESS DATE: 20260515 FILER: COMPANY DATA: COMPANY CONFORMED NAME: DAFNA Capital Management LLC CENTRAL INDEX KEY: 0001389933 ORGANIZATION NAME: EIN: 364334068 FILING VALUES: FORM TYPE: 13F-HR SEC ACT: 1934 Act SEC FILE NUMBER: 028-12327 FILM NUMBER: 26985268 BUSINESS ADDRESS: STREET 1: 10990 WILSHIRE BOULEVARD STREET 2: SUITE 1400 CITY: LOS ANGELES STATE: CA ZIP: 90024 BUSINESS PHONE: (310) 954-3200 MAIL ADDRESS: STREET 1: 10990 WILSHIRE BOULEVARD STREET 2: SUITE 1400 CITY: LOS ANGELES STATE: CA ZIP: 90024 13F-HR 1 primary_doc.xml X0202 13F-HR LIVE false false false 0001389933 XXXXXXXX 03-31-2026 03-31-2026 DAFNA Capital Management LLC

10990 WILSHIRE BOULEVARD SUITE 1400 LOS ANGELES CA 90024

13F HOLDINGS REPORT 028-12327 000129053 801-62559 N Nathan Fischel 310-954-3200 Nathan Fischel Los Angeles CA 05-15-2026 1 83 439591894 false 1 0001389932 028-12328 004732394 Fischel Nathan INFORMATION TABLE 2 DAFNA_information_table.xml ACCURAY INC COM 004397105 652205 1680508 SH SOLE 1680508 0 0 ADC THERAPEUTICS SA SHS H0036K147 270304 72081 SH SOLE 72081 0 0 ADICET BIO INC COM NEW 007002207 638860 93812 SH SOLE 93812 0 0 ALECTOR INC COM 014442107 1952955 908351 SH SOLE 908351 0 0 ALIGN TECHNOLOGY INC COM 016255101 2571450 15000 SH SOLE 15000 0 0 ALKERMES PLC SHS G01767105 4932084 139482 SH SOLE 139482 0 0 ALLOGENE THERAPEUTICS INC COM 019770106 3343088 1370118 SH SOLE 1370118 0 0 ANNEXON INC COM 03589W102 652678 117812 SH SOLE 117812 0 0 AQUESTIVE THERAPEUTICS INC COM 03843E104 1528922 368415 SH SOLE 368415 0 0 ARCUS BIOSCIENCES INC COM 03969F109 9586706 443829 SH SOLE 443829 0 0 ARS PHARMACEUTICALS INC COM 82835W108 1118459 139285 SH SOLE 139285 0 0 ASCENDIS PHARMA A/S NOTE 2.250% 4/0 04351PAD3 5916500 4000000 PRN SOLE 4000000 0 0 ASCENDIS PHARMA A/S SPONSORED ADR 04351P101 5301275 23177 SH SOLE 23177 0 0 ATRICURE INC COM 04963C209 17044706 597431 SH SOLE 597431 0 0 AUTOLUS THERAPEUTICS LTD SPON ADS 05280R100 247456 179316 SH SOLE 179316 0 0 AXOGEN INC COM 05463X106 8281175 249960 SH SOLE 249960 0 0 BICARA THERAPEUTICS INC COM 055477103 8388269 421733 SH SOLE 421733 0 0 BICYCLE THERAPEUTICS PLC SPONSORED ADS 088786108 299243 64492 SH SOLE 64492 0 0 BIOCRYST PHARMACEUTICALS INC COM 09058V103 4095961 430248 SH SOLE 430248 0 0 BIOHAVEN LTD COM G1110E107 7154918 845735 SH SOLE 845735 0 0 BIONTECH SE SPONSORED ADS 09075V102 622160 7000 SH SOLE 7000 0 0 CELLDEX THERAPEUTICS INC COM NEW 15117B202 2173391 68518 SH SOLE 68518 0 0 CENTURY THERAPEUTICS INC COM 15673T100 5501638 2434353 SH SOLE 2434353 0 0 COMPASS PATHWAYS PLC SPONSORED ADS 20451W101 13376417 2418882 SH SOLE 2418882 0 0 COMPUGEN LTD ORD M25722105 549078 257783 SH SOLE 257783 0 0 CYBIN INC COM NEW 23256X407 2392133 498361 SH SOLE 498361 0 0 CYTOKINETICS INC COM NEW 23282W605 14335227 217497 SH SOLE 217497 0 0 CYTOMX THERAPEUTICS INC COM 23284F105 1081000 230000 SH SOLE 230000 0 0 DAY ONE BIOPHARMACEUTICALS I COM 23954D109 20978247 978463 SH SOLE 978463 0 0 DENALI THERAPEUTICS INC COM 24823R105 6115200 318500 SH SOLE 318500 0 0 DEXCOM INC COM 252131107 5418321 86279 SH SOLE 86279 0 0 EDGEWISE THERAPEUTICS INC COM 28036F105 3535434 112236 SH SOLE 112236 0 0 ENGENE HOLDINGS INC COM 29286M105 1275874 187353 SH SOLE 187353 0 0 FATE THERAPEUTICS INC COM 31189P102 660000 550000 SH SOLE 550000 0 0 FOGHORN THERAPEUTICS INC COM 344174107 534686 111859 SH SOLE 111859 0 0 FULCRUM THERAPEUTICS INC COM 359616109 1572350 205000 SH SOLE 205000 0 0 GALAPAGOS NV SPON ADR 36315X101 3905250 130175 SH SOLE 130175 0 0 IBIO INC COM NEW 451033708 367912 193638 SH SOLE 193638 0 0 IDEAYA BIOSCIENCES INC COM 45166A102 15884977 476740 SH SOLE 476740 0 0 IMMATICS NV SHS N44445109 2222462 225860 SH SOLE 225860 0 0 IMMUNOVANT INC COM 45258J102 3739016 150524 SH SOLE 150524 0 0 INOGEN INC COM 45780L104 5223206 845179 SH SOLE 845179 0 0 INSPIRE MEDICAL SYSTEMS INC COM 457730109 938756 18200 SH SOLE 18200 0 0 INSULET CORP COM 45784P101 2280961 10870 SH SOLE 10870 0 0 ISHARES NASDAQ BIOTECH INDX ETF 464287556 10484741 62095 SH SOLE 62095 0 0 KALVISTA PHARMACEUTICALS INC COM 483497103 5382802 267402 SH SOLE 267402 0 0 KARYOPHARM THERAPEUTICS INC COM NEW 48576U205 255106 45800 SH SOLE 45800 0 0 KURA ONCOLOGY INC COM 50127T109 1917607 235868 SH SOLE 235868 0 0 LARIMAR THERAPEUTICS INC COM 517125100 9131238 2029164 SH SOLE 2029164 0 0 LEXEO THERAPEUTICS INC COM 52886X107 2164319 377059 SH SOLE 377059 0 0 MAPLIGHT THERAPEUTICS INC COM 56565P103 3476552 171006 SH SOLE 171006 0 0 MAZE THERAPEUTICS INC COM 578784100 1044750 35000 SH SOLE 35000 0 0 MBX BIOSCIENCES INC COM 55287L101 5237630 175465 SH SOLE 175465 0 0 MEDIWOUND LTD SHS NEW M68830112 1520865 94405 SH SOLE 94405 0 0 MINERALYS THERAPEUTICS INC COM 603170101 1042694 38490 SH SOLE 38490 0 0 NEKTAR THERAPEUTICS COM NEW 640268306 11884557 165178 SH SOLE 165178 0 0 NEUMORA THERAPEUTICS INC COM 640979100 136500 70000 SH SOLE 70000 0 0 NEUROCRINE BIOSCIENCES INC COM 64125C109 9302820 70615 SH SOLE 70615 0 0 NEUROGENE INC COM 64135M105 1141762 56635 SH SOLE 56635 0 0 NEWAMSTERDAM PHARMA CO ORDINARY SHARES N62509109 640200 20000 SH SOLE 20000 0 0 ORCHESTRA BIOMED HOLDINGS INC COM 68572M106 539074 126841 SH SOLE 126841 0 0 ORIC PHARMACEUTICALS INC COM 68622P109 945460 98724 SH SOLE 98724 0 0 ORTHOPEDIATRICS CORP COM 68752L100 1518108 95659 SH SOLE 95659 0 0 PLIANT THERAPEUTICS INC COM 729139105 613620 487000 SH SOLE 487000 0 0 POLYPID LTD COM M8001Q126 910602 207900 SH SOLE 207900 0 0 PROCEPT BIOROBOTICS CORP COM 74276L105 3001200 120000 SH SOLE 120000 0 0 PROFOUND MEDICAL CORP COM NEW 74319B502 1704272 263005 SH SOLE 263005 0 0 PROQR THERAPEUTICS N V SHS EURO N71542109 2539449 1567561 SH SOLE 1567561 0 0 RAPPORT THERAPEUTICS INC COM 75383L102 2346750 75000 SH SOLE 75000 0 0 REVOLUTION MEDICINES INC COM 76155X100 56470936 580678 SH SOLE 580678 0 0 SCYNEXIS INC COM NEW 811292200 996630 1086956 SH SOLE 1086956 0 0 SPDR S&P BIOTECH ETF ETF 78464A870 40682644 318505 SH SOLE 318505 0 0 STEREOTAXIS INC COM NEW 85916J409 25172219 13680554 SH SOLE 13680554 0 0 STOKE THERAPEUTICS INC COM 86150R107 4261290 130875 SH SOLE 130875 0 0 STRUCTURE THERAPEUTICS INC SPONSORED ADS 86366E106 2241300 46500 SH SOLE 46500 0 0 SYNDAX PHARMACEUTICALS INC COM 87164F105 5077413 217355 SH SOLE 217355 0 0 TANDEM DIABETES CARE INC COM NEW 875372203 6809337 355208 SH SOLE 355208 0 0 TELA BIO INC COM 872381108 893438 1441029 SH SOLE 1441029 0 0 ULTRAGENYX PHARMACEUTICAL INC COM 90400D108 1280045 61100 SH SOLE 61100 0 0 VERRICA PHARMACEUTICALS INC COM SHS 92511W207 813136 153712 SH SOLE 153712 0 0 VIKING THERAPEUTICS INC COM 92686J106 1936651 59516 SH SOLE 59516 0 0 XENON PHARMACEUTICALS INC COM 98420N105 14582392 250772 SH SOLE 250772 0 0 ZENAS BIOPHARMA INC COM 98937L105 830875 42500 SH SOLE 42500 0 0