The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ACHILLION PHARMACEUTICALS COM 00448Q201 1,002 630,182 SH   SOLE 630,182 0 0
ADVAXIS INC COM NEW 007624208 317 1,666,666 SH   SOLE 1,666,666 0 0
AERIE PHARMACEUTICALS INC COM 00771V108 5,118 141,770 SH   SOLE 141,770 0 0
AKEBIA THERAPEUTICS INC COM 00972D105 3,957 715,538 SH   SOLE 715,538 0 0
ALDER BIOPHARMACEUTICALS INC NOTE 2.500% 2/0 014339AA3 201 250,000 PRN   SOLE 250,000 0 0
ALDER BIOPHARMACEUTICALS INC COM 014339105 4,059 396,013 SH   SOLE 396,013 0 0
ALDEYRA THERAPEUTICS INC COM 01438T106 415 50,000 SH   SOLE 50,000 0 0
APPLIED GENETIC TECHNOL CORP COM 03820J100 894 359,190 SH   SOLE 359,190 0 0
APTINYX INC COM 03836N103 240 14,500 SH   SOLE 14,500 0 0
ARBUTUS BIOPHARMA CORP COM 03879J100 946 246,900 SH   SOLE 246,900 0 0
ARCTURUS THERAPEUTICS LTD SHS M1492T105 330 72,805 SH   SOLE 72,805 0 0
ARDELYX INC COM 039697107 846 472,859 SH   SOLE 472,859 0 0
ARENA PHARMACEUTICALS INC COM NEW 040047607 3,659 93,942 SH   SOLE 93,942 0 0
ARGENX SE SPONSORED ADR 04016X101 5,601 58,300 SH   SOLE 58,300 0 0
ARQULE INC COM 04269E107 1,268 457,664 SH   SOLE 457,664 0 0
ASCENDIS PHARMA A S SPONSORED ADR 04351P101 4,839 77,242 SH   SOLE 77,242 0 0
ASSEMBLY BIOSCIENCES INC COM 045396108 1,144 50,573 SH   SOLE 50,573 0 0
ATRICURE INC COM 04963C209 9,753 318,729 SH   SOLE 318,729 0 0
BELLICUM PHARMACEUTICALS INC COM 079481107 88 30,000 SH   SOLE 30,000 0 0
BIOCRYST PHARMACEUTICALS INC COM 09058V103 3,748 464,415 SH   SOLE 464,415 0 0
BIOHAVEN PHARMACEUTICALS HOLD COM G11196105 2,958 80,000 SH   SOLE 80,000 0 0
BIOTELEMETRY INC COM 090672106 2,556 42,800 SH   SOLE 42,800 0 0
BIOTIME INC COM 09066L105 91 100,000 SH   SOLE 100,000 0 0
BLUEBIRD BIO INC COM 09609G100 2,678 27,000 SH   SOLE 27,000 0 0
BLUEPRINT MEDICINES CORP COM 09627Y109 4,997 92,691 SH   SOLE 92,691 0 0
CARA THERAPEUTICS INC COM 140755109 1,867 143,611 SH   SOLE 143,611 0 0
CARDIOVASCULAR SYSTEMS INC COM 141619106 1,886 66,200 SH   SOLE 66,200 0 0
CIDARA THERAPEUTICS INC COM 171757107 500 212,766 SH   SOLE 212,766 0 0
CONCERT PHARMACEUTICALS INC COM 206022105 1,326 105,656 SH   SOLE 105,656 0 0
CORBUS PHARMACEUTICALS HLDGS COM 21833P103 905 155,000 SH   SOLE 155,000 0 0
CYMABAY THERAPEUTICS INC COM 23257D103 2,617 332,511 SH   SOLE 332,511 0 0
CYTOKINETICS INC COM NEW 23282W605 1,174 185,826 SH   SOLE 185,826 0 0
DERMIRA INC COM 24983L104 72 10,000 SH   SOLE 10,000 0 0
DEXCOM INC COM 252131107 4,073 34,000 SH   SOLE 34,000 0 0
DEXCOM INC NOTE 0.750% 5/1 252131AF4 336 250,000 PRN   SOLE 250,000 0 0
DICERNA PHARMACEUTICALS INC COM 253031108 1,267 118,500 SH   SOLE 118,500 0 0
FOAMIX PHARMACEUTICALS LTD SHS M46135105 2,901 808,000 SH   SOLE 808,000 0 0
GALAPAGOS NV SPON ADR 36315X101 3,817 41,609 SH   SOLE 41,609 0 0
IMMUNOMEDICS INC COM 452907108 1,174 82,254 SH   SOLE 82,254 0 0
INCYTE CORP COM 45337C102 1,367 21,500 SH   SOLE 21,500 0 0
INSULET CORP NOTE 1.375% 45784PAG6 1,590 1,500,000 PRN   SOLE 1,500,000 0 0
INTEC PHARMA LTD JERUSALEM SHS M53644106 3,493 463,228 SH   SOLE 463,228 0 0
ISHARES TR NASDAQ BIOTECH ETF 464287556 6,258 64,900 SH   SOLE 64,900 0 0
JOHNSON AND JOHNSON COM 478160104 1,213 9,400 SH   SOLE 9,400 0 0
KADMON HOLDINGS INC COM 48283N106 136 65,500 SH   SOLE 65,500 0 0
KALVISTA PHARMACEUTICALS INC COM 483497103 399 20,225 SH   SOLE 20,225 0 0
KURA ONCOLOGY INC COM 50127T109 2,087 148,617 SH   SOLE 148,617 0 0
LEAP THERPEUTICS INC COM 52187K101 340 170,000 SH   SOLE 170,000 0 0
LOXO ONCOLOGY INC COM 548862101 25,447 181,675 SH   SOLE 181,675 0 0
LUMINEX CORP COM 55027E102 3,198 138,391 SH   SOLE 138,391 0 0
MACROGENICS INC COM 556099109 994 78,305 SH   SOLE 78,305 0 0
MADRIGAL PHARMACEUTICALS INC COM 558868105 744 6,600 SH   SOLE 6,600 0 0
MASIMO CORPORATION COM 574795100 322 3,000 SH   SOLE 3,000 0 0
MENLO THERAPEUTICS INC COM 586858102 2,227 540,637 SH   SOLE 540,637 0 0
MINERVA NEUROSCIENCES INC COM 603380106 176 26,084 SH   SOLE 26,084 0 0
NATUS MEDICAL INC COM 639050103 1,290 37,900 SH   SOLE 37,900 0 0
NEOS THERAPEUTICS INC COM 64052L106 45 27,500 SH   SOLE 27,500 0 0
NEUROCRINE BIOSCIENCES INC COM 64125C109 3,928 55,008 SH   SOLE 55,008 0 0
NEVRO CORP COM 64157F103 1,214 31,210 SH   SOLE 31,210 0 0
NXSTAGE MEDICAL INC COM 67072V103 8,933 312,119 SH   SOLE 312,119 0 0
OBSEVA SA COM H5861P103 561 44,338 SH   SOLE 44,338 0 0
ORAMED PHARMACEUTICALS INC COM NEW 68403P203 48 16,000 SH   SOLE 16,000 0 0
PHASEBIO PHARMACEUTICALS INC COM 717224109 309 100,000 SH   SOLE 100,000 0 0
PROQR THERAPEUTICS N V SHS EURO N71542109 4,300 272,474 SH   SOLE 272,474 0 0
PROTEOSTASIS THERAPEUTICS INC COM 74373B109 177 54,569 SH   SOLE 54,569 0 0
RADIUS HEALTH INC COM NEW 750469207 338 20,500 SH   SOLE 20,500 0 0
RADIUS HEALTH INC NOTE 3.000% 9/0 750469AA6 3,064 4,000,000 PRN   SOLE 4,000,000 0 0
RIGEL PHARMACEUTICALS INC COM NEW 766559603 316 137,600 SH   SOLE 137,600 0 0
SAGE THERAPEUTICS INC COM 78667J108 9,991 104,306 SH   SOLE 104,306 0 0
SCYNEXIS INC COM 811292101 613 1,272,927 SH   SOLE 1,272,927 0 0
SOL GEL TECHNOLOGIES LTD SHS M8694L103 211 35,000 SH   SOLE 35,000 0 0
SPERO THERAPEUTICS INC COM 84833T103 431 70,000 SH   SOLE 70,000 0 0
STEREOTAXIS INC COM 85916J409 14,789 13,680,554 SH   SOLE 13,680,554 0 0
SUTRO BIOPHARMA INC COM 869367102 284 31,494 SH   SOLE 31,494 0 0
TRANSLATE BIO INC COM 89374L104 1,717 228,939 SH   SOLE 228,939 0 0
UROGEN PHARMA LTD COM M96088105 646 15,000 SH   SOLE 15,000 0 0
VALERITAS HOLDINGS INC COM NEW 91914N202 431 1,325,000 SH   SOLE 1,325,000 0 0
VBI VACCINES INC COM NEW 91822J103 1,360 850,000 SH   SOLE 850,000 0 0
VIKING THERAPEUTICS INC COM 92686J106 1,371 179,200 SH   SOLE 179,200 0 0
WAVE LIFE SCIENCES LTD SHS Y95308105 2,014 47,900 SH   SOLE 47,900 0 0
XENON PHARMACEUTICALS INC COM 98420N105 1,500 237,683 SH   SOLE 237,683 0 0
ZAFGEN INC COM 98885E103 358 72,279 SH   SOLE 72,279 0 0
ZOGENIX INC COM NEW 98978L204 5,242 143,764 SH   SOLE 143,764 0 0