The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE

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COLUMN 1COLUMN 2COLUMN 3COLUMN 4COLUMN 5COLUMN 6COLUMN 7COLUMN 8
VALUESHRS ORSH/PUT/INVESTMENTOTHERVOTING AUTHORITY
NAME OF ISSUERTITLE OF CLASSCUSIP(x$1000)PRN AMTPRNCALLDISCRETIONMANAGERSOLESHAREDNONE
ACHILLION PHARMACEUTICALSCOM00448Q2011,002630,182SH SOLE 630,18200
ADVAXIS INCCOM NEW0076242083171,666,666SH SOLE 1,666,66600
AERIE PHARMACEUTICALS INCCOM00771V1085,118141,770SH SOLE 141,77000
AKEBIA THERAPEUTICS INCCOM00972D1053,957715,538SH SOLE 715,53800
ALDER BIOPHARMACEUTICALS INCNOTE 2.500% 2/0014339AA3201250,000PRN SOLE 250,00000
ALDER BIOPHARMACEUTICALS INCCOM0143391054,059396,013SH SOLE 396,01300
ALDEYRA THERAPEUTICS INCCOM01438T10641550,000SH SOLE 50,00000
APPLIED GENETIC TECHNOL CORPCOM03820J100894359,190SH SOLE 359,19000
APTINYX INCCOM03836N10324014,500SH SOLE 14,50000
ARBUTUS BIOPHARMA CORPCOM03879J100946246,900SH SOLE 246,90000
ARCTURUS THERAPEUTICS LTDSHSM1492T10533072,805SH SOLE 72,80500
ARDELYX INCCOM039697107846472,859SH SOLE 472,85900
ARENA PHARMACEUTICALS INCCOM NEW0400476073,65993,942SH SOLE 93,94200
ARGENX SESPONSORED ADR04016X1015,60158,300SH SOLE 58,30000
ARQULE INCCOM04269E1071,268457,664SH SOLE 457,66400
ASCENDIS PHARMA A SSPONSORED ADR04351P1014,83977,242SH SOLE 77,24200
ASSEMBLY BIOSCIENCES INCCOM0453961081,14450,573SH SOLE 50,57300
ATRICURE INCCOM04963C2099,753318,729SH SOLE 318,72900
BELLICUM PHARMACEUTICALS INCCOM0794811078830,000SH SOLE 30,00000
BIOCRYST PHARMACEUTICALS INCCOM09058V1033,748464,415SH SOLE 464,41500
BIOHAVEN PHARMACEUTICALS HOLDCOMG111961052,95880,000SH SOLE 80,00000
BIOTELEMETRY INCCOM0906721062,55642,800SH SOLE 42,80000
BIOTIME INCCOM09066L10591100,000SH SOLE 100,00000
BLUEBIRD BIO INCCOM09609G1002,67827,000SH SOLE 27,00000
BLUEPRINT MEDICINES CORPCOM09627Y1094,99792,691SH SOLE 92,69100
CARA THERAPEUTICS INCCOM1407551091,867143,611SH SOLE 143,61100
CARDIOVASCULAR SYSTEMS INCCOM1416191061,88666,200SH SOLE 66,20000
CIDARA THERAPEUTICS INCCOM171757107500212,766SH SOLE 212,76600
CONCERT PHARMACEUTICALS INCCOM2060221051,326105,656SH SOLE 105,65600
CORBUS PHARMACEUTICALS HLDGSCOM21833P103905155,000SH SOLE 155,00000
CYMABAY THERAPEUTICS INCCOM23257D1032,617332,511SH SOLE 332,51100
CYTOKINETICS INCCOM NEW23282W6051,174185,826SH SOLE 185,82600
DERMIRA INCCOM24983L1047210,000SH SOLE 10,00000
DEXCOM INCCOM2521311074,07334,000SH SOLE 34,00000
DEXCOM INCNOTE 0.750% 5/1252131AF4336250,000PRN SOLE 250,00000
DICERNA PHARMACEUTICALS INCCOM2530311081,267118,500SH SOLE 118,50000
FOAMIX PHARMACEUTICALS LTDSHSM461351052,901808,000SH SOLE 808,00000
GALAPAGOS NVSPON ADR36315X1013,81741,609SH SOLE 41,60900
IMMUNOMEDICS INCCOM4529071081,17482,254SH SOLE 82,25400
INCYTE CORPCOM45337C1021,36721,500SH SOLE 21,50000
INSULET CORPNOTE 1.375%45784PAG61,5901,500,000PRN SOLE 1,500,00000
INTEC PHARMA LTD JERUSALEMSHSM536441063,493463,228SH SOLE 463,22800
ISHARES TR NASDAQ BIOTECHETF4642875566,25864,900SH SOLE 64,90000
JOHNSON AND JOHNSONCOM4781601041,2139,400SH SOLE 9,40000
KADMON HOLDINGS INCCOM48283N10613665,500SH SOLE 65,50000
KALVISTA PHARMACEUTICALS INCCOM48349710339920,225SH SOLE 20,22500
KURA ONCOLOGY INCCOM50127T1092,087148,617SH SOLE 148,61700
LEAP THERPEUTICS INCCOM52187K101340170,000SH SOLE 170,00000
LOXO ONCOLOGY INCCOM54886210125,447181,675SH SOLE 181,67500
LUMINEX CORPCOM55027E1023,198138,391SH SOLE 138,39100
MACROGENICS INCCOM55609910999478,305SH SOLE 78,30500
MADRIGAL PHARMACEUTICALS INCCOM5588681057446,600SH SOLE 6,60000
MASIMO CORPORATIONCOM5747951003223,000SH SOLE 3,00000
MENLO THERAPEUTICS INCCOM5868581022,227540,637SH SOLE 540,63700
MINERVA NEUROSCIENCES INCCOM60338010617626,084SH SOLE 26,08400
NATUS MEDICAL INCCOM6390501031,29037,900SH SOLE 37,90000
NEOS THERAPEUTICS INCCOM64052L1064527,500SH SOLE 27,50000
NEUROCRINE BIOSCIENCES INCCOM64125C1093,92855,008SH SOLE 55,00800
NEVRO CORPCOM64157F1031,21431,210SH SOLE 31,21000
NXSTAGE MEDICAL INCCOM67072V1038,933312,119SH SOLE 312,11900
OBSEVA SACOMH5861P10356144,338SH SOLE 44,33800
ORAMED PHARMACEUTICALS INCCOM NEW68403P2034816,000SH SOLE 16,00000
PHASEBIO PHARMACEUTICALS INCCOM717224109309100,000SH SOLE 100,00000
PROQR THERAPEUTICS N VSHS EURON715421094,300272,474SH SOLE 272,47400
PROTEOSTASIS THERAPEUTICS INCCOM74373B10917754,569SH SOLE 54,56900
RADIUS HEALTH INCCOM NEW75046920733820,500SH SOLE 20,50000
RADIUS HEALTH INCNOTE 3.000% 9/0750469AA63,0644,000,000PRN SOLE 4,000,00000
RIGEL PHARMACEUTICALS INCCOM NEW766559603316137,600SH SOLE 137,60000
SAGE THERAPEUTICS INCCOM78667J1089,991104,306SH SOLE 104,30600
SCYNEXIS INCCOM8112921016131,272,927SH SOLE 1,272,92700
SOL GEL TECHNOLOGIES LTDSHSM8694L10321135,000SH SOLE 35,00000
SPERO THERAPEUTICS INCCOM84833T10343170,000SH SOLE 70,00000
STEREOTAXIS INCCOM85916J40914,78913,680,554SH SOLE 13,680,55400
SUTRO BIOPHARMA INCCOM86936710228431,494SH SOLE 31,49400
TRANSLATE BIO INCCOM89374L1041,717228,939SH SOLE 228,93900
UROGEN PHARMA LTDCOMM9608810564615,000SH SOLE 15,00000
VALERITAS HOLDINGS INCCOM NEW91914N2024311,325,000SH SOLE 1,325,00000
VBI VACCINES INCCOM NEW91822J1031,360850,000SH SOLE 850,00000
VIKING THERAPEUTICS INCCOM92686J1061,371179,200SH SOLE 179,20000
WAVE LIFE SCIENCES LTDSHSY953081052,01447,900SH SOLE 47,90000
XENON PHARMACEUTICALS INCCOM98420N1051,500237,683SH SOLE 237,68300
ZAFGEN INCCOM98885E10335872,279SH SOLE 72,27900
ZOGENIX INCCOM NEW98978L2045,242143,764SH SOLE 143,76400