The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ACHILLION PHARMACEUTICALS COM 00448Q201 1,223 266,500 SH   SOLE 266,500 0 0
ADAMIS PHARMACEUTICALS CORP COM NEW 00547W208 127 24,401 SH   SOLE 24,401 0 0
ADVAXIS INC COM NEW 007624208 1,603 247,000 SH   SOLE 247,000 0 0
AEGLEA BIOTHERAPEUTICS INC COM 00773J103 1,346 349,592 SH   SOLE 349,592 0 0
AERIE PHARMACEUTICALS INC COM 00771V108 5,611 106,770 SH   SOLE 106,770 0 0
AFFIMED N V COM N01045108 190 92,500 SH   SOLE 92,500 0 0
AKEBIA THERAPEUTICS INC COM 00972D105 1,951 135,738 SH   SOLE 135,738 0 0
ALDER BIOPHARMACEUTICALS INC COM 014339105 2,531 221,013 SH   SOLE 221,013 0 0
ANAPTYSBIO INC COM 032724106 132 5,500 SH   SOLE 5,500 0 0
APPLIED GENETIC TECHNOL CORP COM 03820J100 2,147 421,000 SH   SOLE 421,000 0 0
ARDELYX INC COM 039697107 1,904 373,409 SH   SOLE 373,409 0 0
ARENA PHARMACEUTICALS INC COM NEW 040047607 262 15,550 SH   SOLE 15,550 0 0
ARGENX SE SPONSORED ADR 04016X101 848 40,000 SH   SOLE 40,000 0 0
ARQULE INC COM 04269E107 973 784,508 SH   SOLE 784,508 0 0
ARRAY BIOPHARMA INC COM 04269X105 167 20,000 SH   SOLE 20,000 0 0
ASCENDIS PHARMA A S SPONSORED ADR 04351P101 922 33,214 SH   SOLE 33,214 0 0
ATRICURE INC COM 04963C209 9,316 384,145 SH   SOLE 384,145 0 0
BEIGENE LTD SPONSORED ADR 07725L102 3,287 73,036 SH   SOLE 73,036 0 0
BELLICUM PHARMACEUTICALS INC COM 079481107 234 20,000 SH   SOLE 20,000 0 0
BIOCRYST PHARMACEUTICALS INC COM 09058V103 3,287 591,128 SH   SOLE 591,128 0 0
BIOLINERX LTD SPONSORED ADR 09071M106 828 980,352 SH   SOLE 980,352 0 0
BIOTELEMETRY INC COM 090672106 2,509 75,000 SH   SOLE 75,000 0 0
BLUEBIRD BIO INC COM 09609G100 840 8,000 SH   SOLE 8,000 0 0
BLUEPRINT MEDICINES CORP COM 09627Y109 4,155 82,000 SH   SOLE 82,000 0 0
CASCADIAN THERAPEUTICS INC COM NEW 14740B606 436 117,310 SH   SOLE 117,310 0 0
CELLECTIS S A SPONSORED ADR 15117K103 1,973 76,404 SH   SOLE 76,404 0 0
CIDARA THERAPEUTICS INC COM 171757107 1,563 208,458 SH   SOLE 208,458 0 0
COGENTIX MEDICAL INC COM 19243A104 615 353,482 SH   SOLE 353,482 0 0
CONATUS PHARMACEUTICALS INC COM 20600T108 288 50,000 SH   SOLE 50,000 0 0
CYMABAY THERAPEUTICS INC COM 23257D103 110 19,067 SH   SOLE 19,067 0 0
DERMIRA INC COM 24983L104 2,200 75,500 SH   SOLE 75,500 0 0
DERMIRA INC NOTE 3.000% 5/1 24983LAA2 1,665 1,500,000 PRN   SOLE 1,500,000 0 0
DEXCOM INC DBCV 0.750% 5/1 252131AE7 254 250,000 PRN   SOLE 250,000 0 0
EDGE THERAPEUTICS INC COM 279870109 199 19,400 SH   SOLE 19,400 0 0
EIGER BIOPHARMACEUTICALS INC COM 28249U105 284 35,977 SH   SOLE 35,977 0 0
EXACTECH INC COM 30064E109 689 23,136 SH   SOLE 23,136 0 0
FOAMIX PHARMACEUTICALS LTD SHS M46135105 1,650 355,667 SH   SOLE 355,667 0 0
GALAPAGOS NV SPON ADR 36315X101 2,954 38,609 SH   SOLE 38,609 0 0
GALENA BIOPHARMA INC COM NEW 363256504 27 46,145 SH   SOLE 46,145 0 0
GEMPHIRE THERAPEUTICS INC COM 36870A108 394 30,797 SH   SOLE 30,797 0 0
IMMUNOMEDICS INC COM 452907108 5,631 637,700 SH   SOLE 637,700 0 0
INOTEK PHARMACEUTICALS CORP NOTE 5.750% 8/0 45780VAB8 369 600,000 PRN   SOLE 600,000 0 0
INOTEK PHARMACEUTICALS CORP COM 45780V102 451 237,135 SH   SOLE 237,135 0 0
INSULET CORP COM 45784P101 3,257 63,484 SH   SOLE 63,484 0 0
INSULET CORP NOTE 2.000% 6/1 45784PAD3 2,746 2,250,000 PRN   SOLE 2,250,000 0 0
IRONWOOD PHARMACEUTICALS INC DBCV 2.250% 6/1 46333XAD0 767 573,000 PRN   SOLE 573,000 0 0
ISHARES TR NASDQ BIOTEC ETF 464287556 2,698 8,700 SH   SOLE 8,700 0 0
JOHNSON AND JOHNSON COM 478160104 1,244 9,400 SH   SOLE 9,400 0 0
LOXO ONCOLOGY INC COM 548862101 24,347 303,621 SH   SOLE 303,621 0 0
MACROGENICS INC COM 556099109 2,087 119,200 SH   SOLE 119,200 0 0
MASIMO CORPORATION COM 574795100 388 4,250 SH   SOLE 4,250 0 0
MINERVA NEUROSCIENCES INC COM 603380106 2,445 276,317 SH   SOLE 276,317 0 0
NATUS MDICAL INC DEL COM 639050103 295 7,900 SH   SOLE 7,900 0 0
NEOS THERAPEUTICS INC COM 64052L106 1,532 209,873 SH   SOLE 209,873 0 0
NEUROCRINE BIOSCIENCES INC COM 64125C109 2,507 54,508 SH   SOLE 54,508 0 0
NEURODERM LTD ORD SHS M74231107 1,134 37,938 SH   SOLE 37,938 0 0
NXSTAGE MEDICAL INC COM 67072V103 5,418 216,119 SH   SOLE 216,119 0 0
OBSEVA SA COM H5861P103 214 25,000 SH   SOLE 25,000 0 0
PROTALIX BIOTHERAPEUTICS INC NOTE 4.500% 9/1 74365AAB7 1,936 2,500,000 PRN   SOLE 2,500,000 0 0
RADIUS HEALTH INC COM NEW 750469207 2,411 53,309 SH   SOLE 53,309 0 0
RIGEL PHARMACEUTICALS INC COM NEW 766559603 1,211 443,478 SH   SOLE 443,478 0 0
SANGAMO THERAPEUTICS INC COM 800677106 1,980 225,000 SH   SOLE 225,000 0 0
SCYNEXIS INC COM 811292101 907 506,900 SH   SOLE 506,900 0 0
SIERRA ONCOLOGY INC COM 82640U107 310 265,000 SH   SOLE 265,000 0 0
SPECTRANETICS CORP COM 84760C107 2,146 55,896 SH   SOLE 55,896 0 0
SPRING BANK PHARMACEUTICALS COM 849431101 217 1,600 SH   SOLE 16,000 0 0
STEREOTAXIS INC COM 85916J409 796 1,372,862 SH   SOLE 1,372,862 0 0
SUNESIS PHARMACEUTICALS INC COM PAR 867328700 2,296 850,328 SH   SOLE 850,328 0 0
SYNERON MEDICAL LTD ORD SHS M87245102 941 85,947 SH   SOLE 85,947 0 0
TANDEM DIABETES CARE INC COM 875372104 579 724,286 SH   SOLE 724,286 0 0
TRILLIUM THERAPEUTICS INC COM NEW 89620X506 88 20,000 SH   SOLE 20,000 0 0
UNIQURE N V SHS N90064101 1,262 203,907 SH   SOLE 203,907 0 0
VOYAGER THERAPEUTICS INC COM 92915B106 1,835 204,808 SH   SOLE 204,808 0 0
XENON PHARMACEUTICALS INC COM 98420N105 1,190 377,695 SH   SOLE 377,695 0 0
ZOGENIX INC COM NEW 98978L204 809 55,809 SH   SOLE 55,809 0 0