The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
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COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP FIGI (to the nearest dollar) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
2SEVENTY BIO INC COMMON STOCK 901384107   1,262,001 429,252 SH   SOLE   429,252 0 0
ACCURAY INC COM 004397105   2,420,269 1,222,358 SH   SOLE   1,222,358 0 0
ACELYRIN INC COM 00445A100   276,285 87,989 SH   SOLE   87,989 0 0
ACRIVON THERAPEUTICS INC COMMON STOCK 004890109   676,732 112,414 SH   SOLE   112,414 0 0
ADC THERAPEUTICS SA SHS H0036K147   445,921 224,081 SH   SOLE   224,081 0 0
ADICET BIO INC COM 007002108   577,200 600,000 SH   SOLE   600,000 0 0
ALECTOR INC COM 014442107   1,725,434 912,928 SH   SOLE   912,928 0 0
ALIGN TECHNOLOGY INC COM 016255101   1,146,805 5,500 SH   SOLE   5,500 0 0
ALKERMES PLC SHS G01767105   3,471,332 120,700 SH   SOLE   120,700 0 0
ALLOGENE THERAPEUTICS INC COM 019770106   2,641,451 1,240,118 SH   SOLE   1,240,118 0 0
APREA THERAPEUTICS INC COM NEW 03836J201   451,302 137,174 SH   SOLE   137,174 0 0
AQUESTIVE THERAPEUTICS INC COM 03843E104   452,120 127,000 SH   SOLE   127,000 0 0
ARCUS BIOSCIENCES INC COM 03969F109   3,785,291 254,217 SH   SOLE   254,217 0 0
ARS PHARMACEUTICALS INC COM 82835W108   936,735 88,790 SH   SOLE   88,790 0 0
ASCENDIS PHARMA A/S NOTE 2.250% 4/0 04351PAD3   4,412,500 4,000,000 PRN   SOLE   4,000,000 0 0
ASCENDIS PHARMA A/S SPONSORED ADR 04351P101   14,228,883 103,355 SH   SOLE   103,355 0 0
ASTRIA THERAPEUTICS INC COM 04635X102   2,679,989 299,775 SH   SOLE   299,775 0 0
ATRICURE INC COM 04963C209   19,609,527 641,673 SH   SOLE   641,673 0 0
AUTOLUS THERAPEUTICS PLC SPON ADS 05280R100   1,378,667 586,667 SH   SOLE   586,667 0 0
AXOGEN INC COM 05463X106   13,956,615 846,882 SH   SOLE   846,882 0 0
BICARA THERAPEUTICS INC COM 055477103   1,837,810 105,500 SH   SOLE   105,500 0 0
BICYCLE THERAPEUTICS PLC SPONSORED ADS 088786108   1,691,186 120,799 SH   SOLE   120,799 0 0
BIOCRYST PHARMACEUTICALS INC COM 09058V103   5,015,840 667,000 SH   SOLE   667,000 0 0
BIOHAVEN LTD COM G1110E107   8,225,777 220,235 SH   SOLE   220,235 0 0
BIOMX INC COM NEW 09090D301   292,869 401,136 SH   SOLE   401,136 0 0
BIONTECH SE SPONSORED ADS 09075V102   968,575 8,500 SH   SOLE   8,500 0 0
BLACK DIAMOND THERAPEUTICS I COM 09203E105   299,600 140,000 SH   SOLE   140,000 0 0
BLUEPRINT MEDICINES CORP COM 09627Y109   13,062,329 149,763 SH   SOLE   149,763 0 0
BRAINSWAY LTD SPONSORED ADS 10501L106   1,821,951 193,208 SH   SOLE   193,208 0 0
CENTESSA PHARMACEUTICALS PLC SPONSORED ADS 152309100   794,838 47,453 SH   SOLE   47,453 0 0
CENTURY THERAPEUTICS INC COM 15673T100   1,721,274 1,704,232 SH   SOLE   1,704,232 0 0
COMPASS PATHWAYS PLC SPONSORED ADS 20451W101   919,334 243,210 SH   SOLE   243,210 0 0
COMPASS THERAPEUTICS INC COM 20454B104   229,671 158,394 SH   SOLE   158,394 0 0
COMPUGEN LTD ORD M25722105   684,219 447,202 SH   SOLE   447,202 0 0
CYTOKINETICS INC COM NEW 23282W605   18,726,624 398,100 SH   SOLE   398,100 0 0
DAY ONE BIOPHARMACEUTICALS I COM 23954D109   9,266,369 731,363 SH   SOLE   731,363 0 0
DEXCOM INC COM 252131107   5,097,979 65,552 SH   SOLE   65,552 0 0
EDGEWISE THERAPEUTICS INC COM 28036F105   4,996,638 187,140 SH   SOLE   187,140 0 0
FOGHORN THERAPEUTICS INC COM 344174107   881,304 186,717 SH   SOLE   186,717 0 0
GALAPAGOS NV SPON ADR 36315X101   3,579,813 130,175 SH   SOLE   130,175 0 0
GOSSAMER BIO INC COM 38341P102   1,274,818 1,409,262 SH   SOLE   1,409,262 0 0
IDEAYA BIOSCIENCES INC COM 45166A102   12,819,854 498,827 SH   SOLE   498,827 0 0
IMMATICS NV SHS N44445109   1,741,950 245,000 SH   SOLE   245,000 0 0
IMMUNOVANT INC COM 45258J102   2,675,061 107,996 SH   SOLE   107,996 0 0
INOGEN INC COM 45780L104   1,914,604 208,790 SH   SOLE   208,790 0 0
INSULET CORP COM 45784P101   3,237,268 12,400 SH   SOLE   12,400 0 0
ISHARES NASDAQ BIOTECH INDX ETF 464287556   13,551,525 102,500 SH   SOLE   102,500 0 0
ITEOS THERAPEUTICS INC COM 46565G104   1,446,505 188,347 SH   SOLE   188,347 0 0
KALVISTA PHARMACEUTICALS INC COM 483497103   6,874,913 811,678 SH   SOLE   811,678 0 0
KEROS THERAPEUTICS INC COM 492327101   2,062,902 130,316 SH   SOLE   130,316 0 0
KURA ONCOLOGY INC COM 50127T109   3,905,285 448,368 SH   SOLE   448,368 0 0
LARIMAR THERAPEUTICS INC COM 517125100   1,437,450 371,434 SH   SOLE   371,434 0 0
LEXEO THERAPEUTICS INC COM 52886X107   2,586,486 393,083 SH   SOLE   393,083 0 0
LINEAGE CELL THERAPEUTICS IN COM 53566P109   1,261,965 2,511,374 SH   SOLE   2,511,374 0 0
MASIMO CORP COM 574795100   495,900 3,000 SH   SOLE   3,000 0 0
MEDIWOUND LTD SHS NEW M68830112   1,147,726 64,479 SH   SOLE   64,479 0 0
MERUS N V COM N5749R100   18,998,358 451,804 SH   SOLE   451,804 0 0
MINERALYS THERAPEUTICS INC COM 603170101   1,803,415 146,500 SH   SOLE   146,500 0 0
NEUROCRINE BIOSCIENCES INC COM 64125C109   9,775,448 71,615 SH   SOLE   71,615 0 0
NEUROGENE INC COM 64135M105   1,177,290 51,500 SH   SOLE   51,500 0 0
NEVRO CORP COM 64157F103   141,360 38,000 SH   SOLE   38,000 0 0
PALVELLA THERAPEUTICS INC COM 697947109   857,424 71,452 SH   SOLE   71,452 0 0
PERSPECTIVE THERAPEUTICS INC COM NEW 46489V302   415,239 130,169 SH   SOLE   130,169 0 0
POLYPID LTD COM M8001Q126   885,470 291,273 SH   SOLE   291,273 0 0
PROQR THERAPEUTICS N V SHS EURO N71542109   4,154,037 1,567,561 SH   SOLE   1,567,561 0 0
REGULUS THERAPEUTICS INC COM 75915K309   1,382,816 875,200 SH   SOLE   875,200 0 0
REVOLUTION MEDICINES INC COM 76155X100   27,607,638 631,176 SH   SOLE   631,176 0 0
SAGE THERAPEUTICS INC COM 78667J108   587,526 108,200 SH   SOLE   108,200 0 0
SPDR S&P BIOTECH ETF ETF 78464A870   35,799,300 397,505 SH   SOLE   397,505 0 0
SPERO THERAPEUTICS INC COM 84833T103   128,750 125,000 SH   SOLE   125,000 0 0
STEREOTAXIS INC COM NEW 85916J409   31,191,663 13,680,554 SH   SOLE   13,680,554 0 0
STOKE THERAPEUTICS INC COM 86150R107   1,887,200 171,097 SH   SOLE   171,097 0 0
STRUCTURE THERAPEUTICS INC SPONSORED ADS 86366E106   962,760 35,500 SH   SOLE   35,500 0 0
SUTRO BIOPHARMA INC COM 869367102   804,225 437,079 SH   SOLE   437,079 0 0
SYNDAX PHARMACEUTICALS INC COM 87164F105   7,165,266 542,002 SH   SOLE   542,002 0 0
TANDEM DIABETES CARE INC COM NEW 875372203   8,039,952 223,208 SH   SOLE   223,208 0 0
TAYSHA GENE THERAPIES INC COM SHS 877619106   903,925 522,500 SH   SOLE   522,500 0 0
TELA BIO INC COM 872381108   4,351,908 1,441,029 SH   SOLE   1,441,029 0 0
UROGEN PHARMA LTD COM M96088105   5,245,285 492,515 SH   SOLE   492,515 0 0
VIKING THERAPEUTICS INC COM 92686J106   2,596,124 64,516 SH   SOLE   64,516 0 0
VIR BIOTECHNOLOGY INC COM 92764N102   734,000 100,000 SH   SOLE   100,000 0 0
XENON PHARMACEUTICALS INC COM 98420N105   10,730,569 273,739 SH   SOLE   273,739 0 0