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Note 2 - Summary of Significant Accounting Policies (Tables)
3 Months Ended
Mar. 31, 2020
Notes Tables  
Schedule of Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents [Table Text Block]
   
March 31,
   
December 31,
 
   
2020
   
2019
 
Cash and cash equivalents
  $
5,708
    $
6,937
 
Restricted cash included in Other assets
   
475
     
475
 
Total cash, cash equivalents, and restricted cash in the statements of cash flows
  $
6,183
    $
7,412
 
Schedules of Concentration of Risk, by Risk Factor [Table Text Block]
   
Three Months Ended March 31,
 
Major distribution or collaboration partner
 
2020
   
2019
 
Avenova Direct via Amazon
   
41
%
   
%
Distributor A
   
*
%
   
26
%
Distributor B
   
*
%
   
17
%
Distributor C
   
*
%
   
14
%
   
March 31,
   
December 31,
 
Major distribution or collaboration partner
 
2020
   
2019
 
Avenova Direct via Amazon
   
12
%    
20
%
Distributor A
   
24
%    
28
%
Distributor B
   
10
%    
13
%
Distributor C
   
19
%    
19
%
Schedule of Earnings Per Share, Basic and Diluted [Table Text Block]
   
Three Months Ended March 31,
 
Numerator
 
2020
   
2019
 
Net loss
  $
(1,582
)
  $
(4,189
)
                 
Denominator
 
 
 
 
 
 
 
 
Weighted average shares of common stock outstanding, basic and diluted
   
27,978
     
17,093
 
Net loss per share attributable to common stockholders, basic and diluted
  $
(0.06
)
  $
(0.25
)
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block]
   
As of March 31,
 
(in thousands)
 
2020
   
2019
 
Period end stock options to purchase common stock
   
2,099
     
2,389
 
Period end common stock warrants
   
8,247
     
544
 
     
10,346
     
2,933