Note 14 - License, Collaboration and Distribution Agreements - Changes in Assets and Liabilities (Details) $ in Thousands	12 Months Ended
	Dec. 31, 2019 USD ($)
Contract Liabilities: Deferred Revenue, Balance at beginning of the period	$ 41
Contract Liabilities: Deferred Revenue, additions
Contract Liabilities: Deferred Revenue, deductions	(41)
Contract Liabilities: Deferred Revenue, Balance at the end of the period
Contract Liabilities: Accrued Liabilities,Balance at beginning of the period	1,432
Contract Liabilities: Accrued Liabilities, additions	5,708
Contract Liabilities: Accrued Liabilities, deductions	(6,706)
Contract Liabilities: Accrued Liabilities, Balance at the end of the period	434
Contract Liabilities, Balance at beginning of the period	1,473
Contract Liabilities, additions	5,708
Contract Liabilities, deductions	(6,747)
Contract Liabilities, Balance at the end of the period	$ 434