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Note 3 - Fair Value Measurements - Fair Value of Warrant Liability (Details) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2019
Dec. 31, 2018
Warrant Liability [Member]    
Balance $ 178 $ 1,489
Fair value of warrant liability reclassified to equity-Adoption of ASU 2017-11 (56)  
Increase (decrease) in fair value of liability during the year ended December 31, 2019   1,311
Balance   178
Decrease in fair value during the year ended December 31, 2018   $ (1,311)
Warrant Liability [Member] | July 2011 and October 2015 Warrants [Member]    
Fair value of warrant liability reclassified to equity-Adoption of ASU 2017-11 (553)  
Increase (decrease) in fair value of liability during the year ended December 31, 2019 465  
Decrease in fair value during the year ended December 31, 2018 (465)  
Warrant Liability [Member] | Domestic, Foreign, and Ladenburg Warrants [Member]    
Issuance of liability 5,269  
Increase (decrease) in fair value of liability during the year ended December 31, 2019 (1,214)  
Decrease in fair value during the year ended December 31, 2018 1,214  
Embedded Derivative Liability [Member]    
Issuance of liability 427  
Increase (decrease) in fair value of liability during the year ended December 31, 2019 (424)  
Decrease in fair value during the year ended December 31, 2018 424  
Warrant Liability and Embedded Derivative Liability [Member]    
Balance $ 4,092