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Note 2 - Summary of Significant Accounting Policies (Tables)
12 Months Ended
Dec. 31, 2019
Notes Tables  
Schedule of Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents [Table Text Block]
   
December 31,
   
December 31,
 
   
2019
   
2018
 
Cash and cash equivalents
  $
6,937
    $
3,183
 
Restricted cash included in Other assets
   
475
     
475
 
Total cash, cash equivalents, and restricted cash in the statements of cash flows
  $
7,412
    $
3,658
 
Schedules of Concentration of Risk, by Risk Factor [Table Text Block]
   
Year Ended December 31,
 
Major distribution or collaboration partner
 
2019
   
2018
   
2017
 
Distributer A
   
16
%
   
23
%
   
22
%
Distributer B
   
17
%
   
26
%
   
23
%
Distributer C
   
15
%
   
25
%
   
21
%
Collaborator D
   
*
%
   
*
%
   
10
%
Avenova Direct via Amazon
   
15
%
   
%
   
%
   
Year Ended December 31,
 
Major distribution or collaboration partner
 
2019
   
2018
 
Distributer A
   
28
%    
32
%
Distributer B
   
13
%    
31
%
Distributer C
   
19
%    
23
%
Avenova Direct via Amazon
   
20
%    
%
Schedule of Earnings Per Share, Basic and Diluted [Table Text Block]
   
Year Ended December 31,
 
Numerator
 
2019
   
2018
   
2017
 
Net loss
  $
(9,658
)   $
(6,545
)   $
(7,403
)
Less: Preferred deemed dividend
   
800
     
     
 
Less: Retained earnings reduction related to warrants down round feature triggered
   
29
     
     
 
Net loss attributable to common stockholders, basic
   
(10,487
)    
(6,545
)    
(7,403
)
Less gain on changes in fair value of warrant liability
   
     
1,311
     
 
Net loss attributable to common stockholders, diluted
  $
(10,487
)   $
(7,856
)   $
(7,403
)
                         
Denominator
 
 
 
 
 
 
 
 
 
 
 
 
Weighted average shares outstanding, basic
   
21,641
     
16,921
     
15,324
 
Net loss per share, basic
  $
(0.48
)   $
(0.39
)   $
(0.48
)
                         
Weighted average shares outstanding, basic
   
21,641
     
16,921
     
15,324
 
Effect of dilutive warrants
   
     
137
     
 
Weighted average shares outstanding, diluted
   
21,641
     
17,058
     
15,324
 
Net loss per share, diluted
  $
(0.48
)   $
(0.46
)   $
(0.48
)
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block]
   
Year Ended December 31,
 
   
2019
   
2018
   
2017
 
   
(in thousands)
 
Stock options
   
2,183
     
3,374
     
2,960
 
Stock warrants
   
8,588
     
     
544
 
     
10,771
     
3,374
     
3,504
 
Schedule of New Accounting Pronouncements and Changes in Accounting Principles [Table Text Block]
Prepaid expenses and other current assets (a)
  $
(49
)
Operating lease right-of-use assets
   
2,239
 
Other assets (b)
   
(2
)
Other accrued liabilities (c)
   
(101
)
Operating lease liability
   
1,063
 
Deferred rent
   
(184
)
Operating lease liability - non-current
   
1,410