X0306 4 2016-11-10 0 0001631650 Aimmune Therapeutics, Inc. AIMT 0001389147 DILLY STEPHEN GEORGE AIMMUNE THERAPEUTICS, INC. 8000 MARINA BOULEVARD, SUITE 300 BRISBANE CA 94005-1884 1 1 0 0 See Remarks Common Stock, $0.0001 par value 2016-07-25 5 G 0 E 14447 0.00 A 779755 D Common Stock, $0.0001 par value 2016-07-25 5 G 0 E 14447 0.00 D 51403 I By GRAT 1 Common Stock, $0.0001 par value 2016-07-25 5 G 0 E 14447 0.00 A 14447 I By Wife Common Stock, $0.0001 par value 2016-07-25 5 G 0 E 14447 0.00 D 51403 I By Wife's GRAT 1 Common Stock, $0.0001 par value 2016-08-24 5 G 0 E 14447 0.00 D 765308 D Common Stock, $0.0001 par value 2016-08-24 5 G 0 E 14447 0.00 A 14447 I By GRAT 2 Common Stock, $0.0001 par value 2016-08-24 5 G 0 E 14447 0.00 D 0 I By Wife Common Stock, $0.0001 par value 2016-08-24 5 G 0 E 14447 0.00 A 14447 I By Wife's GRAT 2 Common Stock, $0.0001 par value 2016-11-10 4 S 0 1304 25.00 D 764004 D Common Stock, $0.0001 par value 2016-11-11 4 S 0 23696 25.0249 D 740308 D Common Stock, $0.0001 par value 2016-11-11 4 S 0 25000 25.00 D 715308 D This transaction involved a gift of securities previously held indirectly by Stephen G. Dilly, as Trustee of The Stephen G. Dilly 2015 Grantor Retained Annuity Trust dated June 23, 2015 (the "First Dilly Trust"). Such shares were transferred from the First Dilly Trust to Reporting Person on July 25, 2016. A portion of these shares is subject to a right of repurchase held by the Issuer. Includes 14,447 shares previously held indirectly by the First Dilly Trust. Such shares were transferred from the First Dilly Trust to Reporting Person on July 25, 2016. These shares are held by the First Dilly Trust. Dr. Dilly has sole voting, investment and dispositive power over the shares held by the First Dilly Trust. This transaction involved a gift of securities previously held indirectly by Edwina Lynette Mullens, as Trustee of The Edwina Lynette Mullens 2015 Grantor Retained Annuity Trust dated June 23, 2015 (the "First Mullens Trust"). Such shares were transferred from the First Mullens Trust to Reporting Person's wife on July 25, 2016. Dr. Dilly disclaims beneficial ownership of the shares held by Ms. Mullens. These shares are held by the First Mullens Trust. Ms. Mullens has sole voting, investment and dispositive power over the shares held by the First Mullens Trust. Dr. Dilly disclaims beneficial ownership of the shares held by the First Mullens Trust. This transaction involved a gift of securities previously held directly by Stephen G. Dilly to Stephen G. Dilly, Trustee, The Stephen G. Dilly 2016 Grantor Retained Annuity Trust DTD August 12, 2016 (the "Second Dilly Trust"). Such shares were transferred from Reporting Person to the Second Dilly Trust on August 24, 2016. These shares are held by the Second Dilly Trust. Dr. Dilly has sole voting, investment and dispositive power over the shares held by the Second Dilly Trust. This transaction involved a gift of securities previously held directly by Edwina Lynette Mullens to Edwina Lynette Mullens, Trustee, The Edwina Lynette Mullens 2016 Grantor Retained Annuity Trust DTD August 12, 2016 (the "Second Mullens Trust"). Such shares were transferred from Reporting Person's wife to the Second Mullens Trust on August 24, 2016. Dr. Dilly disclaims beneficial ownership of the shares held by the Second Mullens Trust. These shares are held by the Second Mullens Trust. Ms. Mullens has sole voting, investment and dispositive power over the shares held by the Second Mullens Trust. Dr. Dilly disclaims beneficial ownership of the shares held by the Second Mullens Trust. The sale reported in the Form 4 was effected pursuant to a Rule 10b5 1 trading plan adopted by the Reporting Person. The transaction was executed in multiple trades in prices ranging from $25.00 to $25.17, inclusive. The price reported in Column 4 above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide upon request to the SEC staff, the Issuer, or a stockholder of the Issuer, information regarding the number of shares and prices at which the transaction was effected. President and Chief Executive Officer /s/ Warren L. DeSouza, as Attorney-in-Fact for Stephen G. Dilly 2016-11-15