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Liquidity - Additional Information (Detail) (USD $)
Mar. 31, 2015
Dec. 31, 2014
Liquidity [Abstract]    
Cash, cash equivalents and investments $ 174,100,000us-gaap_CashCashEquivalentsAndShortTermInvestments  
Accumulated deficit $ (363,254,000)us-gaap_RetainedEarningsAccumulatedDeficit $ (348,719,000)us-gaap_RetainedEarningsAccumulatedDeficit