X0206 3 2016-10-19 0 0001388658 iRhythm Technologies, Inc. IRTC 0001384771 SYNERGY LIFE SCIENCE PARTNERS L P 1350 BAYSHORE HIGHWAY, SUITE 920 BURLINGAME CA 94010 0 0 1 0 0001584405 Synergy Venture Partners, LLC 1350 BAYSHORE HIGHWAY, SUITE 920 BURLINGAME CA 94010 0 0 1 0 0001584404 Jain Mudit K. 1350 BAYSHORE HIGHWAY, SUITE 920 BURLINGAME CA 94010 0 0 1 0 0001584403 Stack Richard S. 1350 BAYSHORE HIGHWAY, SUITE 920 BURLINGAME CA 94010 0 0 1 0 0001324130 Starling William N JR 1350 BAYSHORE HIGHWAY, SUITE 920 BURLINGAME CA 94010 0 0 1 0 Series A Convertible Preferred Stock Common Stock 1555500 D Series A Convertible Preferred Stock Common Stock 4925751 D Series A Convertible Preferred Stock Common Stock 3111000 D Series B Convertible Preferred Stock Common Stock 398659 D Series C Convertible Preferred Stock Common Stock 225649 D Series C Convertible Preferred Stock Common Stock 477524 D Series D Convertible Preferred Stock Common Stock 1053072 D Series E Convertible Preferred Stock Common Stock 670735 D Series E Convertible Preferred Stock Common Stock 332412 D Series D Preferred Stock Warrant (Right to Buy) 0.001 2019-11-01 Common Stock 291672 D Immediately N/A The number of underlying shares of common stock reported in column 3 does not reflect a 5.882698 for 1 reverse stock split, to be effective upon the closing of the issuer's initial public offering. 1-for-1 Synergy Venture Partners, LLC ("SVP LLC") serves as the sole General Partner of Synergy Life Science Partners, LP ("Synergy"). As such, SVP LLC possesses sole voting and investment control over the securities owned by Synergy, and may be deemed to have indirect beneficial ownership of the securities held by Synergy. SVP LLC, however, owns no securities of the Issuer directly. Messrs. Stack, Jain and Starling are Managers of SVP LLC and share voting and dispositive power over the shares held by Synergy. Each Reporting Person disclaims beneficial ownership of the shares held by Synergy except to the extent of his or its proportionate pecuniary interest therein. Converts into common stock on a 2.00438849 for 1 basis. Converts into common stock on a 2.24685484 for 1 basis. The Date of Event is based upon the date of effectiveness of the Issuer's Registration Statement on Form S-1 filed in connection with the Issuer's initial public offering, estimated to be on or about October 19, 2016. /s/ William N. Starling, Jr., Synergy Life Science Partners, LP 2016-10-19 /s/ William N. Starling, Jr., Synergy Venture Partners, LLC 2016-10-19 /s/ Mudit Jain, Synergy Venture Partners, LLC 2016-10-19 /s/ Richard Stack, Synergy Venture Partners, LLC 2016-10-19