The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete. | |||||||||||||||||
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UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 13F FORM 13F INFORMATION TABLE |
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| COLUMN 1 | COLUMN 2 | COLUMN 3 | COLUMN 4 | COLUMN 5 | COLUMN 6 | COLUMN 7 | COLUMN 8 | ||||
| VALUE | SHRS OR | SH/ | PUT/ | INVESTMENT | OTHER | VOTING AUTHORITY | |||||
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | (x$1000) | PRN AMT | PRN | CALL | DISCRETION | MANAGER | SOLE | SHARED | NONE |
| AERIE PHARMACEUTICALS INC | COM | 00771V108 | 16,195 | 670,036 | SH | SOLE | 670,036 | 0 | 0 | ||
| AKEBIA THERAPEUTICS INC | COM | 00972D105 | 19,592 | 3,100,000 | SH | SOLE | 3,100,000 | 0 | 0 | ||
| AMICUS THERAPEUTICS INC | COM | 03152W109 | 22,576 | 2,317,870 | SH | SOLE | 2,317,870 | 0 | 0 | ||
| APPLE INC | COM | 037833100 | 78,636 | 267,788 | SH | SOLE | 267,788 | 0 | 0 | ||
| BIOHAVEN PHARMACTL HLDG CO L | COM | G11196105 | 1,954 | 35,900 | SH | SOLE | 35,900 | 0 | 0 | ||
| BLUEPRINT MEDICINES CORP | COM | 09627Y109 | 13,672 | 170,667 | SH | SOLE | 170,667 | 0 | 0 | ||
| BROOKFIELD ASSET MGMT INC | CL A LTD VT SH | 112585104 | 38,879 | 672,652 | SH | SOLE | 672,652 | 0 | 0 | ||
| CABLE ONE INC | COM | 12685J105 | 95,183 | 63,947 | SH | SOLE | 63,947 | 0 | 0 | ||
| CORVUS PHARMACEUTICALS INC | COM | 221015100 | 15,926 | 2,927,560 | SH | SOLE | 2,927,560 | 0 | 0 | ||
| CRINETICS PHARMACEUTICALS IN | COM | 22663K107 | 3,387 | 135,009 | SH | SOLE | 135,009 | 0 | 0 | ||
| ENTASIS THERAPEUTICS HLDGS I | COM | 293614103 | 10,844 | 2,181,843 | SH | SOLE | 2,181,843 | 0 | 0 | ||
| FLEXION THERAPEUTICS INC | COM | 33938JAB2 | 9,315 | 450,000 | SH | SOLE | 450,000 | 0 | 0 | ||
| GALERA THERAPEUTICS INC | COM | 36338D108 | 44,863 | 3,409,021 | SH | SOLE | 3,409,021 | 0 | 0 | ||
| INOGEN INC | COM | 45780L104 | 242,525 | 3,549,321 | SH | SOLE | 3,549,321 | 0 | 0 | ||
| INSPIRE MED SYS INC | COM | 457730109 | 12,987 | 175,000 | SH | SOLE | 175,000 | 0 | 0 | ||
| INTERSECT ENT INC | COM | 46071F103 | 5,421 | 217,709 | SH | SOLE | 217,709 | 0 | 0 | ||
| MILESTONE PHARMACEUTICALS INC | COM | 59935V107 | 38,976 | 2,434,470 | SH | SOLE | 2,434,470 | 0 | 0 | ||
| MIRUM PHARMACEUTICALS INC | COM | 604749101 | 59,955 | 2,445,147 | SH | SOLE | 2,445,147 | 0 | 0 | ||
| MORPHIC HLDG INC | COM | 61775R105 | 45,396 | 2,645,446 | SH | SOLE | 2,645,446 | 0 | 0 | ||
| MYOKARDIA INC | COM | 62857M105 | 2,212 | 30,348 | SH | SOLE | 30,348 | 0 | 0 | ||
| NEURONETICS INC | COM | 64131A105 | 3,307 | 736,578 | SH | SOLE | 736,578 | 0 | 0 | ||
| PROTAGONIST THERAPEUTICS INC | COM | 74366E102 | 3,377 | 479,074 | SH | SOLE | 479,074 | 0 | 0 | ||
| SEASPINE HLDGS CORP | COM | 81255T108 | 15,710 | 1,308,037 | SH | SOLE | 1,308,037 | 0 | 0 | ||
| SI BONE INC | COM | 825704109 | 19,193 | 892,684 | SH | SOLE | 892,684 | 0 | 0 | ||
| SILK ROAD MEDICAL INC | COM | 82710M100 | 9,893 | 245,000 | SH | SOLE | 245,000 | 0 | 0 | ||
| SPERO THERAPEUTICS INC | COM | 84833T103 | 8,948 | 931,099 | SH | SOLE | 931,099 | 0 | 0 | ||
| VANGUARD INDEX FDS | TOTAL STK MKT | 922908769 | 707,689 | 4,325,200 | SH | SOLE | 4,325,200 | 0 | 0 | ||
| VERONA PHARMA PLC | SPONSORED ADS | 925050106 | 4,259 | 740,740 | SH | SOLE | 740,740 | 0 | 0 | ||
| ZOGENIX INC | COM NEW | 98978L204 | 1,861 | 35,700 | SH | SOLE | 35,700 | 0 | 0 | ||