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Leasehold Improvements and Equipment, Net
 12 Months Ended
Dec. 31, 2022
Property, Plant and Equipment [Abstract]  
Leasehold Improvements and Equipment, Net Leasehold Improvements and Equipment, Net
Leasehold improvements and equipment for the periods indicated consisted of the following:
December 31,
(In thousands)20222021
Laboratory equipment$3,268 $3,281 
Leasehold improvements2,060 2,387 
Computer equipment602 814 
Implementation costs - cloud computing arrangements1,075 771 
Furniture and fixtures176 203 
Construction in progress172 91 
7,353 7,547 
Less: Accumulated depreciation(4,554)(4,544)
Leasehold improvements and equipment, net $2,799 $3,003 
Depreciation expense on leasehold improvements and equipment for the years ended December 31, 2022 and 2021 was approximately $869,000 and $890,000, respectively. Depreciation is computed using the straight-line method over the estimated useful lives of the depreciable assets (ranging from three to ten years). Leasehold improvements are amortized on a straight-line basis over the shorter of their estimated useful lives or the remaining lease term.
During the year ended December 31, 2022, the Company retired or disposed certain leasehold improvements and equipment resulting in a loss of $7,000. At the time of retirement or disposal, the related cost and accumulated depreciation were removed from the respective accounts.