Condensed Consolidated Balance Sheets (USD $) In Thousands, unless otherwise specified	Jun. 30, 2012	Dec. 31, 2011
Assets
Cash and cash equivalents	$ 6,514	$ 9,148
Short-term investments	15,188	25,161
Trade receivable	708	1,166
Receivable from collaborative partner	20	502
Inventories	68	654
Prepaid expenses and other current assets	1,049	1,364
Restricted cash	160	160
Total current assets	23,707	38,155
Property and equipment, net	333	547
Restricted cash	252	251
Other assets	342	274
Total Assets	24,634	39,227
Liabilities and Stockholders' Deficit
Accounts payable	707	1,321
Accrued compensation	1,045	2,084
Accrued research and development	208	282
Other accrued expenses	1,006	2,245
Deferred product revenue, net	648	1,075
Deferred collaborative revenue	7,242	7,261
Long-term obligations-current portion	8,233	4,829
Total current liabilities	19,089	19,097
Non-current liabilities
Deferred collaborative revenue	21,507	25,098
Other long-term liabilities	133	146
Long term obligations, net of current portion	64,231	62,746
Total non-current liabilities	85,871	87,990
Commitments and contingencies
Stockholders' deficit:
Common Stock, $0.001 par value: Authorized shares - 100,000,000 at June 30, 2012 and December 31, 2011 Issued and outstanding shares - at 33,201,869 June 30, 2012 and 29,897,186 at December 31, 2011	33	30
Additional paid-in capital	242,359	238,181
Accumulated other comprehensive (loss) income	(1)	1
Accumulated deficit	(322,717)	(306,072)
Total stockholders' deficit	(80,326)	(67,860)
Total liabilities and stockholders' deficit	$ 24,634	$ 39,227