Consolidated Balance Sheets (USD $) In Thousands, unless otherwise specified	Dec. 31, 2011	Dec. 31, 2010
Assets
Cash and cash equivalents	$ 9,148	$ 8,705
Short-term investments	25,161	38,125
Trade receivable	1,166	607
Receivable from collaboration partner	502	65
Inventories	654	786
Prepaid expenses and other current assets	1,364	1,082
Restricted cash	160	290
Total current assets	38,155	49,660
Property and equipment, net	547	809
Restricted cash	251	120
Other assets	274	261
Total assets	39,227	50,850
Liabilities and Stockholders' Deficit
Accounts payable	1,321	1,544
Accrued compensation	2,084	1,867
Accrued research and development	282	582
Other accrued expenses	2,245	3,011
Deferred product revenue, net	1,075	577
Deferred collaboration revenue	7,261	7,242
Long-term obligations-current portion	4,829	2,222
Total current liabilities	19,097	17,045
Non-current liabilities:
Deferred collaboration revenue	25,098	32,359
Other long-term liabilities	146	115
Long-term obligations	62,746	42,622
Total non-current liabilities	87,990	75,096
Commitments and contingencies
Stockholders' deficit:
Common stock, $0.001 par value; 100,000,000 shares authorized at December 31, 2011 and 2010; 29,897,186 and 17,869,108 shares issued and outstanding at December 31, 2011 and 2010, respectively	30	18
Additional paid-in capital	238,181	215,220
Accumulated other comprehensive income (loss)	1	(2)
Accumulated deficit	(306,072)	(256,527)
Total stockholders' deficit	(67,860)	(41,291)
Total liabilities and stockholders' deficit	$ 39,227	$ 50,850