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License Agreements (Details) - USD ($)
$ in Millions
1 Months Ended
Oct. 31, 2017
Feb. 29, 2016
Settlement Agreement and Associated License Agreement, 2014, Shire LLC, New Drug Application    
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]    
License agreement, up-front, non-refundable license fee paid, maximum   $ 1.0
License Agreement, 2017, Shire LLC, New Drug Application    
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]    
License agreement, up-front, non-refundable license fee paid, maximum $ 1.0