<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0609</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2026-08-03</periodOfReport>

    <issuer>
        <issuerCik>0001385613</issuerCik>
        <issuerName>GREENLIGHT CAPITAL RE, LTD.</issuerName>
        <issuerTradingSymbol>GLRE</issuerTradingSymbol>
        <issuerForeignTradingSymbol></issuerForeignTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001240451</rptOwnerCik>
            <rptOwnerName>EINHORN DAVID</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerNonUSAddressFlag>false</rptOwnerNonUSAddressFlag>
            <rptOwnerStreet1>140 EAST 45TH STREET</rptOwnerStreet1>
            <rptOwnerStreet2>24TH FLOOR</rptOwnerStreet2>
            <rptOwnerCity>NEW YORK</rptOwnerCity>
            <rptOwnerState>NY</rptOwnerState>
            <rptOwnerZipCode>10017</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>true</isDirector>
            <isTenPercentOwner>true</isTenPercentOwner>
        </reportingOwnerRelationship>
    </reportingOwner>

    <aff10b5One>false</aff10b5One>

    <nonDerivativeTable>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Ordinary Shares</value>
            </securityTitle>
            <transactionDate>
                <value>2026-08-03</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>D</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
                <footnoteId id="F1"/>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>106060</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>16.1435</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>D</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>1284428</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>By Trust</value>
                    <footnoteId id="F1"/>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
        <nonDerivativeHolding>
            <securityTitle>
                <value>Ordinary Shares</value>
            </securityTitle>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>4864227</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>By LLC</value>
                    <footnoteId id="F2"/>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeHolding>
    </nonDerivativeTable>

    <footnotes>
        <footnote id="F1">These shares are held by the David M. Einhorn 2021-07 Family Trust, a family trust, the beneficiaries of which are the Reporting Person's children. On August 3, 2026, pursuant to the Ordinary Share Repurchase Agreement between Greenlight Capital Re, Ltd. and the David M. Einhorn 2021-07 Family Trust, the Issuer purchased 106,060 ordinary shares from the David M. Einhorn 2021-07 Family Trust.</footnote>
        <footnote id="F2">These shares are held by DME 2022 Holdings LLC (the &quot;LLC&quot;). The Reporting Person is the sole Manager of the LLC, and interests in the LLC are held by a family trust the beneficiaries of which are the Reporting Person's children.</footnote>
    </footnotes>

    <remarks>* The Power of Attorney executed by David Einhorn, authorizing the signatory to sign and file this report on David Einhorn's behalf, filed as Exhibit 99.1 to the Schedule 13D filed with the Securities and Exchange Commission on August 29, 2019 by David Einhorn and other reporting persons with respect to the common units of CONSOL Coal Resources LP, is hereby incorporated by reference. David Einhorn is a Director of Greenlight Capital Re, Ltd. For purposes of Section 16 of the Securities Exchange Act of 1934, as amended, the beneficial owners of the shares reported herein are deemed directors by deputization by virtue of their representation on the Board of Directors of Greenlight Capital Re, Ltd. David Einhorn disclaims beneficial ownership of the ordinary shares report-ed herein except to the extent of his pecuniary interests therein.</remarks>

    <ownerSignature>
        <signatureName>/s/ Daniel Roitman, attorney-in-fact for David Einhorn*</signatureName>
        <signatureDate>2026-08-04</signatureDate>
    </ownerSignature>
</ownershipDocument>
