Commitments and Contingencies - License Agreement (Details)			12 Months Ended
	Oct. 26, 2020 USD ($)	Jun. 22, 2017 USD ($) payment trading_day	Dec. 31, 2021 USD ($)	Dec. 31, 2020 USD ($)
Other Commitments [Line Items]
License agreement cost		$ 250,000
Royalty expenses			$ 9,066,432	$ 6,196,706
Development program cost	$ 5,200,000
Payment for development costs			900,000
Severance costs				1,200,000
License Agreement
Other Commitments [Line Items]
Upfront payments | payment		2
Percent of upfront payments which may be paid by issuing common stock		50.00%
Percent of average share price		75.00%
Threshold trading days | trading_day		20
Maximum additional product milestone payments		$ 1,800,000
Maximum additional commercialization milestone payments		$ 5,000,000
Termination advance notice period		30 days
Royalty expenses			$ 0	$ 0
Supply Agreement
Other Commitments [Line Items]
Other commitment, period		20 years
Material cure period		60 days