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Stockholder's Equity
 12 Months Ended
Dec. 31, 2021
Stockholders' Equity Note [Abstract]  
Stockholders' Equity Stockholder's Equity
Common Stock
During the year ended December 31, 2021
Common Stock

    During the year ended December 31, 2021 the Company issued 448,847 shares of Common Stock as a result of employee stock option exercises, and received net cash proceeds of approximately $2.7 million.
During the year ended December 31, 2021 the Company issued 19,902 shares of Common Stock as a result of vesting of employee restricted stock.
During the year ended December 31, 2021 the Company issued 155,916 shares of Common Stock as a result of conversion of debt to equity at a conversion price of $19.64 per share.
During the year ended December 31, 2021, the Company issued 27,076 shares of its Common Stock in relation to the cashless exercise of stock options that were granted outside of the Company's 2017 Long-Term Incentive Stock Plan (the "2017 Plan"). A total of 35,000 stock options were exercised at an exercise price of $7.25 per share.
During the year ended December 31, 2020 
Common Stock
    During the year ended December 31, 2020 the Company issued 71,667 shares of Common Stock as a result of employee stock option and warrant exercises, and received net cash proceeds of approximately $0.7 million.
Equity Plans
    On September 8, 2017, the Company held its Annual Meeting of Stockholders (the “Annual Meeting”), at which time the 2017 Plan was approved by stockholder vote. The 2017 Plan allows the Company to grant incentive stock options (“ISOs”), non-qualified stock options (“NSOs”), and restricted stock units ("RSU's") to purchase a maximum of 400,000 shares of the Company's Common Stock. Under the terms of the 2017 Plan, ISOs and restricted stock units may only be granted to Company employees and directors, while NSOs may be granted to employees, directors, advisors, and consultants. The Board has the authority to determine to whom options and will be granted, the number of options, the term, and the exercise price. Options are to be granted at an exercise price not less than fair value for an ISO or an NSO. The vesting period is normally over a period of four years from the vesting date. The contractual term of an option is no longer than ten years. As provided in the 2017 Plan, on January 1, 2021, the number of shares available for issuance was increased by 4% of the Company's outstanding stock as of December 31, 2020, which represents an increase of 170,324 shares. As of December 31, 2021, the Company had 104,255 shares available for future issuance under the 2017 Plan.
    Prior to adopting the 2017 Plan, the Company did not have a formal long-term incentive stock plan. Prior to the implementation of the 2017 Plan, the Company had discretion to provide designated employees of the Company and its affiliates, certain consultants, and advisors who perform services for the Company and its affiliates, and non-employee members of the Board and its affiliates with the opportunity to receive grants of non-qualified stock options (the "Pre-2017 Non-Qualified Stock Options"). All of the Pre-2017 Non-Qualified Stock Option Grants were intended to qualify as non-qualified stock options. There were no Pre-2017 Non-Qualified Stock Option Grants that were intended to qualify as incentive stock options.
On July 8, 2021, the Board of Directors of the Company adopted the 2021 Inducement Equity Incentive Plan (the “Inducement Plan”) and, subject to the adjustment provisions of the Inducement Plan, reserved 100,000 shares of the Company’s Common Stock for issuance pursuant to equity awards granted under the Inducement Plan. On December 9, 2021, the Board of Directors of the Company amended the Inducement Plan to reserve an additional 100,000 shares of the Company’s Common Stock.
    Stock option activity for the Pre-2017 Non-Qualified Stock Options for the years ended December 31, 2021 and 2020, is presented in the table below: 
 Number of
Shares		Weighted-
average
Exercise
Price		Weighted-
average
Remaining
Contractual
Term
(years)		Aggregate
Intrinsic
Value
Outstanding at December 31, 20192,500,500 $7.03 5.05$18,426,325 
Exercised(20,000)$9.50 
Forfeited(15,000)$10.00 
Outstanding at December 31, 20202,465,500 $6.99 4.09$2,773,190 
Exercised(480,002)$5.86 
Forfeited(34,998)$10.00 
Outstanding at December 31, 20211,950,500 $7.17 3.4$51,602,190 
Exercisable at December 31, 20211,950,500 $7.17 3.4$51,602,190 
 
During the years ended December 31, 2021 and 2020, the Company recognized $0 and $1,235 of non-cash expense related to vested Pre-2017 Non-Qualified Stock Options granted in prior periods.
The 2017 Plan
    The assumptions used in the valuation of options granted under the 2017 Plan during the years ended December 31, 2021 and 2020 were as follows:
Year Ended December 31, 2021Year Ended December 31, 2020
Market value of stock on measurement date
$8.20 to $24.75
$8.79 to $13.60
Risk-free interest rate
0.50% to 1.30%
0.33% to 1.68%
Dividend yield— %— %
Volatility factor
76% to 89%
91% to 101%
Term (years)
5.5 to 6.25
5.5 to 6.25

    Stock option activity for options granted under the 2017 Plan during the years ended December 31, 2021 and 2020 is presented in the table below:
Number of
Shares Outstanding		Weighted-
average
Exercise
Price		Weighted-
average
Remaining
Contractual
Term
(years)		Aggregate
Intrinsic
Value
Outstanding at December 31, 2019491,950 $24.08 8.43$81,888 
Granted191,500 $12.12 
Exercised— — 
Forfeited(71,690)$15.05 
Outstanding at December 31, 2020611,760 $21.39 7.85$— 
Granted163,285 $12.4 
Exercised(3,845)$19.49 
Forfeited(12,142)$12.60 
Balance at December 31, 2021759,058 $19.61 7.31$10,997,428 
Exercisable at December 31, 2021513,279 $22.84 6.72$5,895,856 
 


During the years ended December 31, 2021 and 2020, the Company recognized approximately $1.7 million and $2.1 million of non-cash expense related to vested options granted during these periods. As of December 31, 2021, there was approximately $1.0 million of unrecognized compensation costs related to non-vested stock options that were granted under the 2017 Plan.
Restricted Stock Units
    Restricted stock activity during the year ended December 31, 2021 is presented in the following table.
Number of SharesGrant Date Fair Value Per Share
Restricted stock units outstanding December 31, 201927,000 $14.51
Restricted stock granted49,600 $12.00
Restricted stock forfeited(27,000)$14.51
Restricted stock units outstanding December 31, 202049,600 $12.00
Restricted stock granted76,268 $12.47
Restricted stock vested(19,902)$10.79
Restricted stock forfeited(1,550)$12.15
Restricted stock units outstanding December 31, 2021104,416 $12.57

    Twenty-five percent (25%) of the restricted stock units will vest on the one year anniversary of the vesting commencement date, and twenty-five percent (25%) will vest annually thereafter on the same day as the vesting commencement date. During the year ended December 31, 2021 and 2020, the Company recognized approximately $0.8 million and $0.2 million of non-cash expense related to restricted stock units. As of December 31, 2021, there was $0.5 million of total unrecognized compensation cost related to restricted stock units.
Inducement Equity Incentive Plan
During 2021, the Company granted options to purchase 56,500 shares of Common Stock, and granted RSUs for 49,800 shares of Common Stock under the Inducement Plan.
The assumptions used in the valuation of options granted under the Inducement Plan during the year ended December 31, 2021 were as follows:
Year Ended December 31, 2021
Market value of stock on measurement date$16.41 
Risk-free interest rate0.84 %
Dividend yield— %
Volatility factor76.26 %
Term (years)6.25

Stock option activity for options granted under the Inducement Plan during the year ended December 31, 2021 is presented in the table below:
Number of Options OutstandingWeighted-average Exercise PriceWeighted-average Remaining Contractual Term (years)Aggregate Intrinsic Value
Balance at December 31, 2020— 
Granted56,500 $16.41 
Exercised— 
Forfeited— 
Balance at December 31, 202156,500 $16.41 9.55$972,930 
During the year ended December 31, 2021, the Company recognized approximately $0.2 million of non-cash expense related to options granted under the Inducement Plan. As of December 31, 2021, there was approximately $0.4 million of total unrecognized compensation cost related to the non-vested stock options that were granted under the 2021 Inducement Equity Incentive Plan.
The following summarizes the restricted stock activity under the Inducement Plan during the year ended December 31, 2021:

Number of SharesWeighted Average Fair Value Per Share
Restricted stock outstanding and unvested at December 31, 2020— 
Restricted stock granted49,800 $26.98 
Restricted stock vested
Restricted stock outstanding and unvested at December 31, 202149,800 $26.98 

During the year ended December 31, 2021, the Company recognized approximately $0.1 million of non-cash expense related to restricted stock units. As of December 31, 2021, there was approximately $1.2 million of total unrecognized compensation cost related to restricted stock units.
Warrants 
    Warrant activity for the years ended December 31, 2021 and 2020 is presented in the table below:
Number of
Warrants		Weighted-
average
Exercise
Price		Weighted-
average
Remaining
Contractual
Term
(years)		Aggregate
Intrinsic
Value
Outstanding at December 31, 2019342,610 $9.77 3.71$1,585,084 
Exercised(59,510)$10.00 
Forfeited(4,300)$10.00 
Outstanding at December 31, 2020278,800 $9.72 3.51$1,164 
Exercised— $— 
Forfeited— $— 
Outstanding at December 31, 2021278,800 $9.72 2.51$6,665,644 
Exercisable at December 31, 2021278,800 $9.72 2.51$6,665,644