Commitments - Heroin In-License Vaccine (Details) - License Royalty Commitment - USD ($)	1 Months Ended	3 Months Ended
	Oct. 31, 2016	Mar. 31, 2019
Other Commitments [Line Items]
Percentage of royalty net sales	3.00%
Percentage of royalty sublicensed	4.00%
Payments for minimum annual royalty	$ 10,000
Agreement expense		$ 0
Maximum
Other Commitments [Line Items]
Fixed milestone payments	$ 715,700