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Commitments - Heroin In-License Vaccine (Details) - License Royalty Commitment - USD ($)
1 Months Ended 3 Months Ended
Oct. 31, 2016
Mar. 31, 2018
Mar. 31, 2017
Other Commitments [Line Items]      
Percentage of royalty net sales 3.00%    
Percentage of royalty sublicensed 4.00%    
Payments for minimum annual royalty $ 10,000    
Payments for royalties 60,000    
Payments for royalties, execution fee 50,000    
Royalty expense, monthly rate   $ 833  
Royalty Expense   $ 3,000 $ 0
Minimum      
Other Commitments [Line Items]      
Payments for royalties 10,000    
Maximum      
Other Commitments [Line Items]      
Fixed milestone payments $ 715,700