<?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/ownership" xmlns:ns2="http://www.sec.gov/edgar/common">
    <headerData>
        <submissionType>144</submissionType>
        <filerInfo>
            <filer>
                <filerCredentials>
                    <cik>0001385250</cik>
                    <ccc>XXXXXXXX</ccc>
                </filerCredentials>
            </filer>
            <liveTestFlag>LIVE</liveTestFlag>



        </filerInfo>
    </headerData>
    <formData>
        <issuerInfo>
            <issuerCik>0000798528</issuerCik>
            <issuerName>ODYSSEY MARINE EXPLORATION, INC.</issuerName>
            <secFileNumber>001-31895</secFileNumber>
            <issuerAddress>
                <ns2:street1>205 S. HOOVER BLVD., SUITE 210</ns2:street1>
                <ns2:city>Tampa</ns2:city>
                <ns2:stateOrCountry>FL</ns2:stateOrCountry>
                <ns2:zipCode>33609</ns2:zipCode>
            </issuerAddress>
            <issuerContactPhone>8138761776</issuerContactPhone>
            <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>MARK D GORDON</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
            <relationshipsToIssuer>
                <relationshipToIssuer>Director</relationshipToIssuer>
                <relationshipToIssuer>Officer</relationshipToIssuer>
            </relationshipsToIssuer>
        </issuerInfo>
        <securitiesInformation>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <brokerOrMarketmakerDetails>
                <name>Morgan Stanley Smith Barney LLC Executive Financial Services</name>
                <address>
                    <ns2:street1>1 New York Plaza</ns2:street1>
                    <ns2:street2>8th Floor</ns2:street2>
                    <ns2:city>New York</ns2:city>
                    <ns2:stateOrCountry>NY</ns2:stateOrCountry>
                    <ns2:zipCode>10004</ns2:zipCode>
                </address>
            </brokerOrMarketmakerDetails>
            <noOfUnitsSold>20956</noOfUnitsSold>
            <aggregateMarketValue>59095.92</aggregateMarketValue>
            <noOfUnitsOutstanding>45190598</noOfUnitsOutstanding>
            <approxSaleDate>10/13/2025</approxSaleDate>
            <securitiesExchangeName>NASDAQ</securitiesExchangeName>
        </securitiesInformation>
        <securitiesToBeSold>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <acquiredDate>12/13/2006</acquiredDate>
            <natureOfAcquisitionTransaction>Restricted Stock Units</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>20956</amountOfSecuritiesAcquired>
            <paymentDate>12/13/2006</paymentDate>
            <natureOfPayment>N/A</natureOfPayment>
        </securitiesToBeSold>
        <nothingToReportFlagOnSecuritiesSoldInPast3Months>Y</nothingToReportFlagOnSecuritiesSoldInPast3Months>
        <remarks>The securities to be sold were acquired upon the vesting of restricted stock units during the period of 12/13/2006 through 12/26/2016. Sales that were executed on October 13, 2025 are being reported on this Form 144 filed on October 14, 2025 given the EDGAR system was not accepting filings on October 13, 2025 in observance of the federal holiday.
</remarks>
        <noticeSignature>
            <noticeDate>10/13/2025</noticeDate>
            <planAdoptionDates>
                <planAdoptionDate>05/15/2025</planAdoptionDate>
            </planAdoptionDates>
            <signature>/s/ Mark D Gordon</signature>
        </noticeSignature>
    </formData>
</edgarSubmission>
