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Note 6 - Commitments and Contingencies (Details Textual)
3 Months Ended 9 Months Ended 21 Months Ended
Sep. 30, 2020
USD ($)
Sep. 30, 2019
USD ($)
Sep. 30, 2019
USD ($)
Sep. 30, 2020
USD ($)
Dec. 31, 2019
USD ($)
Jun. 30, 2015
ft²
Operating Lease, Expense $ 500,000 $ 500,000 $ 1,400,000 $ 1,400,000    
Headquarters and Laboratory Facilities in South San Francisco, California [Member]            
Area of Real Estate Property (Square Foot) | ft²           59,000
Headquarters and Laboratory Facilities in South San Francisco, California [Member] | Other Noncurrent Assets [Member]            
Security Deposit 603,000     603,000 $ 603,000  
Laboratory and Office Space in Austin, Texas [Member] | Other Noncurrent Assets [Member]            
Security Deposit $ 139,000     $ 139,000 $ 139,000