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Genzyme Co-promotion Agreement (Details)
1 Months Ended 3 Months Ended 7 Months Ended 9 Months Ended 10 Months Ended 12 Months Ended 14 Months Ended 31 Months Ended
Jan. 01, 2015
Feb. 29, 2012
USD ($)
Sep. 30, 2015
USD ($)
Sep. 30, 2014
USD ($)
Jul. 31, 2014
USD ($)
Sep. 30, 2015
USD ($)
Sep. 30, 2014
USD ($)
Dec. 31, 2014
USD ($)
Dec. 31, 2012
Feb. 27, 2014
Aug. 11, 2014
Feb. 28, 2015
country
Jan. 31, 2012
country
Genzyme Co-promotion Agreement                          
Amortization of up-front co-promotion fee           $ 1,423,000 $ 1,794,000            
Co-promotion agreement | Genzyme                          
Genzyme Co-promotion Agreement                          
Co-promotion expenses     $ 1,800,000 $ 3,200,000   5,200,000 8,700,000            
Outstanding obligation to Genzyme     1,800,000     1,800,000   $ 6,000,000          
Amortization of up-front co-promotion fee     500,000 $ 500,000   1,400,000 $ 1,800,000            
Co-promotion agreement | Genzyme | Accounts payable                          
Genzyme Co-promotion Agreement                          
Outstanding obligation to Genzyme               2,700,000          
Co-promotion agreement | Genzyme | Accrued liabilities                          
Genzyme Co-promotion Agreement                          
Outstanding obligation to Genzyme     $ 1,700,000     $ 1,700,000   $ 3,300,000          
Afirma thyroid diagnostic solution co-promotion agreement | Genzyme                          
Genzyme Co-promotion Agreement                          
Number of countries outside United States for exclusive promotion under the agreement | country                         40
Co-promotion fee received from Genzyme   $ 10,000,000                      
Co-promotion fees as a percentage of cash receipts           15.00%   32.00% 50.00% 40.00%      
Maximum amount to be spent by co-promoter for qualifying clinical development activities in countries that require additional testing         $ 500,000                
Amortization period of co-promotion fee                     4 years    
Ex-U.S. Co-Promotion Agreement | Genzyme                          
Genzyme Co-promotion Agreement                          
Number of countries outside United States for exclusive promotion under the agreement | country                       5  
Co-promotion fee paid as a percentage of net revenue 25.00%                        
Period of agreement 5 years